Atherosclerosis
Volume 170, Issue 1 , Pages 141-146 , September 2003

Remodelling of cerebrospinal fluid lipoproteins after subarachnoid hemorrhage

  • A.D. Kay

      Affiliations

    • Department of Neurosurgery, University of Glasgow, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44-141-201-1100; fax: +44-141-201-2998
  • ,
  • S.P. Day

      Affiliations

    • Department of Pathological Biochemistry, University of Glasgow, 4th Floor Queen Elizabeth building Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, UK
    • Tel.: +44-141-211-4979; fax: +44-141-553-2558.
  • ,
  • J.A.R. Nicoll

      Affiliations

    • Division of Clinical Neurosciences (formerly department of Neuropathology, University of Glasgow), University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK
    • Tel.: +44-2380-79-6634; fax: +44-2380-79-6839.
  • ,
  • C.J. Packard

      Affiliations

    • Department of Pathological Biochemistry, University of Glasgow, 4th Floor Queen Elizabeth building Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, UK
    • Tel.: +44-141-211-4979; fax: +44-141-553-2558.
  • ,
  • M.J. Caslake

      Affiliations

    • Department of Pathological Biochemistry, University of Glasgow, 4th Floor Queen Elizabeth building Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, UK
    • Tel.: +44-141-211-4979; fax: +44-141-553-2558.

Received 20 November 2002 ,Revised 4 June 2003 ,Accepted 11 June 2003.

References 

  1. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988;240:622–630
  2. Mahley RW, Huang Y. Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond. Curr. Opin. Lipidol. 1999;10:207–217
  3. Teasdale GM, Nicoll JA, Murray G, Fiddes M. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet. 1997;350:1069–1071
  4. Alberts MJ, Graffagnino C, McClenny C, DeLong D, Strittmatter W, Saunders AM, et al.  ApoE genotype and survival from intracerebral haemorrhage. Lancet. 1995;346:575
  5. McCarron MO, Muir KW, Nicoll JA, Stewart J, Currie Y, Brown K, et al.  Prospective study of apolipoprotein E genotype and functional outcome following ischemic stroke. Arch. Neurol. 2000;57:1480–1484
  6. Niskakangas T, Ohman J, Niemela M, Ilveskoski E, Kunnas TA, Karhunen PJ. Association of apolipoprotein e polymorphism with outcome after aneurysmal subarachnoid hemorrhage: a preliminary study. Stroke. 2001;32:1181–1184
  7. Dietschy JM, Turley SD. Cholesterol metabolism in the brain. Curr. Opin. Lipidol. 2001;12:105–112
  8. Graham DI, Horsburgh K, Nicoll JA, Teasdale GM. Apolipoprotein E and the response of the brain to injury. Acta Neurochir. Suppl. (Wien). 1999;73:89–92
  9. Horsburgh K, Nicoll JA. Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat. Neuropathol. Appl. Neurobiol. 1996;22:342–349
  10. White F, Nicoll JA, Horsburgh K. Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion. Exp. Neurol. 2001;169:307–318
  11. White F, Nicoll JA, Roses AD, Horsburgh K. Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion. Neurobiol. Dis. 2001;8:611–625
  12. Linton MF, Gish R, Hubl ST, Butler E, Esquivel C, Bry WI, et al.  Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J. Clin. Invest. 1991;88:270–281
  13. Carlsson J, Armstrong VW, Reiber H, Felgenhauer K, Seidel D. Clinical relevance of the quantification of apolipoprotein E in cerebrospinal fluid. Clin. Chim. Acta. 1991;196:167–176
  14. Guyton JR, Miller SE, Martin ME, Khan WA, Roses AD, Strittmatter WJ. Novel large apolipoprotein E-containing lipoproteins of density 1.006–1.060 g/ml in human cerebrospinal fluid. J. Neurochem. 1998;70:1235–1240
  15. Montine KS, Bassett CN, Ou JJ, Markesbery WR, Swift LL, Montine TJ. Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins. J. Lipid Res. 1998;39:2443–2451
  16. LaDu MJ, Reardon C, Van EL, Fagan AM, Bu G, Holtzman D, et al.  Lipoproteins in the central nervous system. Ann. NY Acad. Sci. 2000;903:167–175
  17. Rebeck GW, Alonzo NC, Berezovska O, Harr SD, Knowles RB, Growdon JH, et al.  Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes. Exp. Neurol. 1998;149:175–182
  18. Demeester N, Castro G, Desrumaux C, De GC, Fruchart JC, Santens P, et al.  Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease. J. Lipid Res. 2000;41:963–974
  19. Ryder RE, Hayes TM, Mulligan IP, Kingswood JC, Williams S, Owens DR. How soon after myocardial infarction should plasma lipid values be assessed?. Br. Med. J. (Clin. Res. Ed). 1984;289:1651–1653
  20. Kargman DE, Tuck C, Berglund L, Lin IF, Mukherjee RS, Thompson EV, et al.  Lipid and lipoprotein levels remain stable in acute ischemic stroke: the Northern Manhattan Stroke Study. Atherosclerosis. 1998;139:391–399
  21. Poirier J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci. 1994;17:525–530
  22. B.W. McColl, D.I. Graham, C.J. Weir, F. White, K. Horsburgh, Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype. Am J Pathol 2003 Jan; 162 (1):273–81 2003; 162: 273–81.
  23. Montine TJ, Montine KS, Swift LL. Central nervous system lipoproteins in Alzheimer's disease. Am. J. Pathol. 1997;151:1571–1575
  24. Nicoll JA, Roberts GW, Graham DI. Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nat. Med. 1995;1:135–137
  25. Horsburgh K, Cole GM, Yang F, Savage MJ, Greenberg BD, Gentleman SM, et al.  beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury. Neuropathol. Appl. Neurobiol. 2000;26:124–132
  26. Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, et al.  Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 2000;97:2892–2897
  27. Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, et al.  Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model. Ann. Neurol. 2000;47:739–747
  28. Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, et al.  Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 1999;400:173–177
  29. J.A. Nicoll, D. Wilkinson, C. Holmes, P. Steart, H. Markham, R.O. Weller, Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003 Mar 17; 2003.
  30. S.D. Preston, P.V. Steart, A. Wilkinson, J.A. Nicoll, R.O. Weller, Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain. Neuropathol Appl Neurobiol 2003 April; 29 (2): 106–17 2003; 29: 106–17.
  31. Horsburgh K, McCulloch J, Nilsen M, McCracken E, Large C, Roses AD, et al. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 2000;20:458–462

PII: S0021-9150(03)00249-1

doi: 10.1016/S0021-9150(03)00249-1

Atherosclerosis
Volume 170, Issue 1 , Pages 141-146 , September 2003