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Atherosclerosis
Volume 176, Issue 1
, Pages 27-35
, September 2004
Timing affects the efficacy of LDL immunization on atherosclerotic lesions in apo E (−/−) mice
References
- Immunological responses to oxidized LDL. Free Radic. Biol. Med. 2000;28:1771–1779
- Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits. Arterioscler. Thromb. Vasc. Biol. 1996;16:1074–1079
- . Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler. Thromb. Vasc. Biol. 1998;18:1972–1982
-
.
Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.
Proc. Natl. Acad. Sci. USA. 1995;92:821–825
- Hyperimmunization of apo-E-deflcient mice with homologous malondialdehyde low-density lipoprotein suppresses early atherogenesis. Atherosclerosis. 1998;138:147–152
- . LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2001;21:108–114
- Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J. Clin. Invest. 1997;100:2680–2690
- . Determinants of atherosclerosis in the young. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Am. J. Cardiol. 1998;82:30T–36T
-
High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound.
Circulation. 2001;103:2705–2710
- Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity. Clin. Infect. Dis. 1999;29:281–288
- . Changes in immune function with age. Rheum. Dis. Clin. North Am. 2000;26:455–473
- Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice. Circulation. 1998;97:780–785
- . The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 1999;19:734–742
- . ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 1994;14:133–140
- . Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression. Arterioscler. Thromb. 1994;14:141–147
-
Low density lipoprotein undergoes oxidative modification in vivo.
Proc. Natl. Acad. Sci. USA. 1989;86:1372–1376
-
An animal model to study local oxidation of LDL and its biological effects in the arterial wall.
Arterioscler.Thromb. Vasc. Biol. 1998;18:884–893
- Innate and acquired immunity in atherogenesis. Nat. Med. 2002;8:1218–1226
- . Regulation of monocyte CD36 and thrombospondin-1 expression by soluble mediators. Arterioscler. Thromb. Vasc. Biol. 1996;16:1019–1025
- Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. J. Lipid Res. 2000;41:688–696
- . Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages. J. Lipid Res. 2000;41:376–383
- . IL-4-induced Oxidative Stress Upregulates VCAM-1 Gene Expression in Human Endothelial Cells. J. Mol. Cell Cardiol. 2001;33:83–94
-
Requisite role for interleukin-4 in the acceleration of fatty streaks induced by heat shock protein 65 or Mycobacterium tuberculosis.
Circ. Res. 2000;S6:1203–1210
- . Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J. Clin. Invest. 2002;109:745–753
- . Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor −/− mice. Arterioscler. Thromb. Vasc. Biol. 2002;22:456–461
- . B-lymphocyte deficiency increases atherosclerosis in LDL receptor-null mice. Arterioscler. Thromb. Vasc. Biol. 2002;22:1892–1898
- The uptake of LDL-IC by human macrophages: predominant involvement of the Fc gamma RI receptor. Atherosclerosis. 1997;135:161–170
- . Oxidized LDL-containing immune complexes induce Fc gamma receptor I-mediated mitogen- activated protein kinase activation in THP-1 macrophages. Arterioscler. Thromb. Vasc. Biol. 1999;19:1600–1607
- Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J. Clin. Invest. 2000;105:1731–1740
- Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo. Arterioscler. Thromb. Vasc. Biol. 2001;21:1333–1339
PII: S0021-9150(04)00232-1
doi: 10.1016/j.atherosclerosis.2004.04.016
© 2004 Elsevier Ireland Ltd. All rights reserved.
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Atherosclerosis
Volume 176, Issue 1
, Pages 27-35
, September 2004
