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Atherosclerosis
Volume 185, Issue 2
, Pages 240-245
, April 2006
Statins prevent NF-κB transactivation independently of the IKK-pathway in human endothelial cells
References
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- Culture of human endothelial cells derived from umbilical veins identification by morphologic and immunologic criteria. J Clin Invest. 1973;52:2745–2751
- Cyclosporin A inhibits tissue factor expression in monocytes/macrophages. Blood. 1996;88:3837–3845
- . Singel step method of RNA-isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156–159
- Statins differ in their ability to block NF-κB activation in human blood monocytes. Clin Pharm Therap. 2003;41:397–401
- . Simvastatin supresses LPS-induced Akt phosphorylation in the human monocyte cell line THP-1. J Surg Res. 2004;116:116–120
- Statins inhibit osteoblast migration by inhibiting Rac–Akt signaling. Biochem Biophys Res Commun. 2004;315:636–642
- Reduction of tumor necrosis factor-α (TNF-α) related nuclear factor-κB (NF-κB) translocation but not inhibitorκ-B (Iκ-B)-degradation by Rho protein inhibition in human endothelial cells. Biochem Pharmacol. 2002;64:971–979
- HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI3-kinase/Akt pathway. J Clin Invest. 2001;108:391–397
PII: S0021-9150(05)00394-1
doi: 10.1016/j.atherosclerosis.2005.06.019
© 2005 Elsevier Ireland Ltd. All rights reserved.
« Previous
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Atherosclerosis
Volume 185, Issue 2
, Pages 240-245
, April 2006
