« Previous
Next »
Atherosclerosis
Volume 199, Issue 2
, Pages 408-414
, August 2008
Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women
References
- . Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res. 2005;46:1239–1247
- . The molecular basis of the human serum paraoxonase activity polymorphism. Nat Genet. 1993;3:73–76
- . The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat Genet. 1996;14:334–336
- Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature. 1998;394:284–287
- . The paraoxonase gene family and atherosclerosis. Free Radic Biol Med. 2005;38:153–163
- . Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine at position 191, for the respective A or B allozymes. Am J Hum Genet. 1993;52:598–608
- . Effects of 5′ regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. Am J Hum Genet. 2001;68:1428–1436
- A sandwich enzyme-linked immunosorbent assay for human serum paraoxonase concentration. J Lipid Res. 2000;41:1358–1363
- . The human serum paraoxonase/arylesterase polymorphism. Am J Hum Genet. 1983;35:1126–1138
- . Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics. 1999;9:745–753
- . Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annu Rev Med. 2003;54:371–392
- . Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies. Lancet. 2004;363:689–695
- . Cigarette smoke extract inhibits plasma paraoxonase activity by modification of the enzyme's free thiols. Biochem Biophys Res Commun. 1997;236:289–293
- . Smoking is associated with reduced serum paraoxonase activity and concentration in patients with coronary artery disease. Circulation. 2000;101:2252–2257
- Daily moderate alcohol consumption increases serum paraoxonase activity; a diet-controlled, randomised intervention study in middle-aged men. Atherosclerosis. 1999;147:405–410
- Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype?. Arterioscler Thromb Vasc Biol. 2001;21:1451–1457
- . Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?. Free Radic Biol Med. 2004;37:1317–1323
- Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype. Arterioscler Thromb Vasc Biol. 2000;20:2441–2447
- Low paraoxonase activity predicts coronary events in the Caerphilly prospective study. Circulation. 2003;107:2775–2779
- Troughton JA, Woodside JV, Yarnell JW, et al. Paraoxonase activity and coronary heart disease risk in healthy middle-aged males: the PRIME study. Atherosclerosis 2007
- Prospect-EPIC Utrecht: study design and characteristics of the cohort population. European prospective investigation into cancer and nutrition. Eur J Epidemiol. 2001;17:1047–1053
- Non-transferrin-bound iron and risk of coronary heart disease in postmenopausal women. Circulation. 2006;113:1942–1949
- . Pharmaco-morbidity linkage: a feasibility study comparing morbidity in two pharmacy based exposure cohorts. J Epidemiol Community Health. 1992;46:136–140
- . Genetic and environmental determinants of the PON-1 phenotype. Eur J Clin Invest. 2007;37:187–196
- . A case-cohort design for epidemiologic cohort studies and disease prevention trials. Biometrika. 1986;73:1–11
- . Analysis of case-cohort designs. J Clin Epidemiol. 1999;52:1165–1172
- Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R. Arterioscler Thromb Vasc Biol. 1998;18:1617–1624
- . Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification. FEBS Lett. 1998;423:57–60
- Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities. Circulation. 2000;101:2510–2517
- . Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry. 2005;44:6371–6382
- Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nat Struct Mol Biol. 2004;11:412–419
- . The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases. J Biol Chem. 2006;281:7649–7656
- Regulation of serum paraoxonase activity by genetic, nutritional, and lifestyle factors in the general population. Clin Chem. 2003;49:1491–1497
- Paraoxonase 1 gene polymorphisms in angiographically assessed coronary artery disease: evidence for gender interaction among Brazilians. Clin Chem Lab Med. 2007;45:874–878
- . Postprandial modulation of serum paraoxonase activity and concentration in diabetic and non-diabetic subjects. Nutr Metab Cardiovasc Dis. 2006;16:457–465
- . Serum paraoxonase: effect of the apolipoprotein composition of HDL and the acute phase response. J Lipid Res. 2003;44:780–792
- . Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response. Atherosclerosis. 1998;139:307–315
- . High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection. Circulation. 2001;103:2283–2288
- Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. J Clin Invest. 1995;96:2758–2767
- . Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime. Nat Med. 2002;8:1211–1217
- . Mechanisms of plaque vulnerability and rupture. J Am Coll Cardiol. 2003;41:15S–22S
- Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia. J Lipid Res. 2005;46:445–451
- . Paraoxonase-1 and linoleic acid oxidation in familial hypercholesterolemia. Biochem Biophys Res Commun. 2005;333:787–793
- . Oxidized LDL and HDL: antagonists in atherothrombosis. Faseb J. 2001;15:2073–2084
PII: S0021-9150(07)00739-3
doi: 10.1016/j.atherosclerosis.2007.11.018
© 2007 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Atherosclerosis
Volume 199, Issue 2
, Pages 408-414
, August 2008
