Corrigendum to “Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using in ApoE heterozygote murine model” [Atherosclerosis 197 (2008) 504–514]

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A corrigendum to this article has been requested by the corresponding author of this paper, due to the caption appearing incorrectly in Fig. 3, Fig. 4.

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• Fig. 3. 

  Microscopic cross sections (10μm) of the proximal aortic root were stained with sudan and counterstained with hematoxylin to reveal lipid deposition and quantified by digital morphometry for both ApoE^+/−- IL-6^−/− mice and ApoE^+/−-IL-6^+/− mice maintained on standard chow diet and inoculated weekly with P.g. (CP) (Fig. 3c), on high fat diet and inoculated weekly with vehicle (HS) ((normal saline) Fig. 3f) and on high fat diet and inoculated weekly with P.g. (HP) (Fig. 3i) .The data is presented as percentage of total lumen of the proximal aorta occupied by lesions at 14 weeks and 24 weeks. Values represent mean ±SD, ^*p<0.05 for ApoE^+/−-IL-6^−/− mice as compared to ApoE^+/−-IL-6^+/− mice in same condition on same diet. Abbreviations are as defined in text. Photomicrographs shown are representative images used to obtain the data presented in (Fig. 3c, f, and i), of proximal aortic lesions in ApoE^+/−-IL6^+/− and ApoE^+/−-IL-6^−/− mice maintained on standard chow diet and inoculated weekly P.g. (CP) (Fig. 3a and b), on high fat diet and inoculated weekly with vehicle (normal saline) (HS) (Fig. 3d and e) and on high fat diet and inoculated weekly with P.g. (HP) (Fig. 3g and h) for 24 weeks. Original magnifications 20X. Scale bar represents 0.5mm.

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• Fig. 4. 

  Representative photomicrographs show immunostained sections of macrophage infiltration (MOMA-2 red staining) (Fig. 4a and b), smooth muscle cell (α-SMA red staining) (Fig. 4d and e) and TUNEL positive cells (green spots coinciding with nuclear stain DAPI) (Fig. 4g and h) in atherosclerotic plaques from the aortic sinus of ApoE^+/−-IL6^+/− and ApoE^+/−-IL-6^−/− mice maintained on high fat diet and inoculated weekly with P.g. (HP) for 24 weeks. Quantitative computer-assisted image analysis (as described in material and methods) was used to determine the percentage of macrophage-positive areas (Fig. 4c), smooth muscle cell area (Fig. 4f) and TUNEL/DAPI positive cells (Fig. 4i) in proximal aortic lesions in ApoE^+/−-IL6^+/− and ApoE^+/−-IL-6^−/− mice of all the groups at 24 weeks. Data represent mean ±SD. ^*p<0.05. Original magnifications 100X. Abbreviations are defined in the text. Scale bar represents 0.5mm.

The correct versions of Fig. 3, Fig. 4, appears below.