Atherosclerosis
Volume 204, Issue 1 , Pages 34-39 , May 2009

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta

  • Federica Lodi

      Affiliations

    • Department of Pharmacology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain
    • Hospital Joan March, 08110 Bunyola, Mallorca, Spain
  • ,
  • Rosario Jimenez

      Affiliations

    • Department of Pharmacology, School of Pharmacy, Universidad de Granada, 18071 Granada, Spain
  • ,
  • Laura Moreno

      Affiliations

    • Department of Pharmacology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain
    • Hospital Joan March, 08110 Bunyola, Mallorca, Spain
  • ,
  • Paul A. Kroon

      Affiliations

    • Institute of Food Research, Colney Lane, NR4 7UA Norwich, United Kingdom
  • ,
  • Paul W. Needs

      Affiliations

    • Institute of Food Research, Colney Lane, NR4 7UA Norwich, United Kingdom
  • ,
  • David A. Hughes

      Affiliations

    • Institute of Food Research, Colney Lane, NR4 7UA Norwich, United Kingdom
  • ,
  • Celestino Santos-Buelga

      Affiliations

    • Laboratorio de Nutrición y Bromatologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
  • ,
  • Ana Gonzalez-Paramas

      Affiliations

    • Laboratorio de Nutrición y Bromatologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
  • ,
  • Angel Cogolludo

      Affiliations

    • Department of Pharmacology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain
    • Hospital Joan March, 08110 Bunyola, Mallorca, Spain
  • ,
  • Rocío Lopez-Sepulveda

      Affiliations

    • Department of Pharmacology, School of Pharmacy, Universidad de Granada, 18071 Granada, Spain
  • ,
  • Juan Duarte

      Affiliations

    • Department of Pharmacology, School of Pharmacy, Universidad de Granada, 18071 Granada, Spain
  • ,
  • Francisco Perez-Vizcaino

      Affiliations

    • Department of Pharmacology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain
    • Hospital Joan March, 08110 Bunyola, Mallorca, Spain
    • Corresponding Author InformationCorresponding author at: Department of Pharmacology, School of Medicine, Universidad Complutense de Madrid, Av Complutense s/n, 28040 Madrid, Spain. Tel.: +34 913941477; fax: +34 913941465.

Received 22 January 2008 ,Revised 14 July 2008 ,Accepted 4 August 2008.

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PII: S0021-9150(08)00551-0

doi: 10.1016/j.atherosclerosis.2008.08.007

Atherosclerosis
Volume 204, Issue 1 , Pages 34-39 , May 2009