Atherosclerosis
Volume 205, Issue 1 , Pages 314-318 , July 2009

Inflammation and adverse cardiovascular outcome in patients with renal artery stenosis and peripheral artery disease

  • Oliver Schlager

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
    • Corresponding Author InformationCorresponding author at: Department of Angiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria. Tel.: +43 1404004670; fax: +43 1404004665.
  • ,
  • Jasmin Amighi

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Markus Haumer

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Schila Sabeti

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Petra Dick

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Wolfgang Mlekusch

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Christian Loewe

      Affiliations

    • Department of Radiology, Medical University Vienna, Austria
  • ,
  • Renate Koppensteiner

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Erich Minar

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria
  • ,
  • Martin Schillinger

      Affiliations

    • Department of Angiology, Medical University Vienna, Austria

Received 20 September 2008 ,Revised 16 November 2008 ,Accepted 3 December 2008.

References 

  1. Lusis AJ. Atherosclerosis. Nature. 2000;407(6801):233–241
  2. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115–126
  3. Libby P, Ridker P, Maseri A. Inflammation and atherosclerosis. Circulation. 2002;105:1135–1143
  4. Glass CK, Witztum JL. Atherosclerosis: the road ahead. Cell. 2001;104:503–516
  5. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med. 2002;347:1557–1565
  6. Tracy RP, Lemaitre RN, Psaty BM, et al. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly: results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol. 1997;17:1121–1127
  7. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836–843
  8. Danesh J, Whincup P, Walker M, et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BMJ. 2000;321:199–204
  9. Albert CM, Ma J, Rifai N, Stampfer MJ, Ridker PM. Prospective study of C-reactive protein, homocysteine, and plasma lipid levels as predictors of sudden cardiac death. Circulation. 2002;105:2595–2599
  10. Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA. 2001;285:2481–2485
  11. Schillinger M, Exner M, Amighi J, et al. Joint effects of C-reactive protein and glycated hemoglobin in predicting future cardiovascular events in patients with advanced atherosclerosis. Circulation. 2003;108:2323–2328
  12. Schillinger M, Exner M, Mlekusch W, et al. Inflammation and carotid artery risk for atherosclerosis study (ICARAS). Circulation. 2005;111:2203–2209
  13. Schlager O, Exner M, Mlekusch W, et al. C-reactive protein predicts future cardiovascular adverse events in patients with carotid stenosis. Stroke. 2007;38(4):1263–1268
  14. Schillinger M, Exner M, Mlekusch W, et al. Serum albumin predicts cardiac adverse events in patients with advanced atherosclerosis—interrelation with traditional cardiovascular risk factors. Thromb Haemost. 2004;91(2):610–618
  15. Mui KW, Sleeswijk M, van den Hout H, van Baal J, Navis G, Woittiez AJ. Incidental renal artery stenosis is an independent predictor of mortality in patients with peripheral vascular disease. J Am Soc Nephrol. 2006;17:2069–2074
  16. Conlon PJ, Athirakul K, Kovalik E, et al. Survival in renal vascular disease. J Am Soc Nephrol. 1998;9:252–256
  17. Conlon PJ, Little MA, Pieper K, Mark DB. Severity of renal vascular disease predicts mortality in patients undergoing coronary angiography. Kidney Int. 2001;60:1490–1497
  18. Iglesias JI, Hamburger RJ, Feldman L, Kaufman JS. The natural history of incidental renal artery stenosis in patients with aortoiliac vascular disease. Am J Med. 2000;109:642–647
  19. Leertouwer TC, Pattynama PM, Van den Berg-Huysmans A. Incidental artery stenosis in peripheral vascular disease: a case for treatment?. Kidney Int. 2001;59:1480–1483
  20. Menon V, Greene T, Wang X, et al. C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease. Kidney Int. 2005;68(2):766–772
  21. Stuveling EM, Hillege HL, Bakker SJ, Gans RO, De Jong PE, De Zeeuw D. C-reactive protein is associated with renal function abnormalities in a non-diabetic population. Kidney Int. 2003;63(2):654–661
  22. Park JS, Park JH, Kang JY, et al. Hyperfibrinogenemia is an independent risk factor for atherosclerotic renal artery stenosis. Am J Nephrol. 1999;19(6):649–654
  23. Rundback JH, Sacks D, Kent KC, et al. AHA Councils on Cardiovascular Radiology, Blood Pressure Research, Kidney in Cardiovascular Disease, Cardio-Thoracic and Vascular Surgery, and Clinical Cardiology, and the Society of Interventional Radiology FDA device forum committee. American Heart Association. Guidelines for the reporting of renal artery revascularization in clinical trials. American Heart Association. Circulation. 2002;106:1572–1585
  24. Stuveling EM, Hillege HL, Bakker SJ, et al. C-reactive protein and microalbuminuria differ in their association with various domains of vascular disease. Atherosclerosis. 2004;172:107–114
  25. Dzielinska Z, Januszewicz A, Demkow M, et al. Cardiovascular risk factors in hypertensive patients with coronary artery disease and coexisting renal artery stenosis. J Hypertens. 2007;25(3):663–670
  26. Fried LF, Shlipak MG, Crump C, et al. Renal insufficiency as a predictor of cardiovascular outcomes and mortality in elderly individuals. J Am Coll Cardiol. 2003;41:1364–1372
  27. Manjunath G, Tighiouart H, Ibrahim H, et al. Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community. J Am Coll Cardiol. 2003;41:47–55
  28. Weiner DE, Tighiouart H, Amin MG, et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol. 2004;15:1307–1315
  29. Panichi V, Migliori M, De Pietro S, et al. The link of biocompatibility to cytokine production. Kidney Int Suppl. 2000;76:S96–S103
  30. Verhave JC, Hillege HL, Burgerhof JG, et al. The association between atherosclerotic risk factors and renal function in the general population. Kidney Int. 2005;67(5):1967–1973
  31. Shlipak MG, Fried L, Crump C, et al. Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency. Circulation. 2003;107:87–92

PII: S0021-9150(08)00852-6

doi: 10.1016/j.atherosclerosis.2008.12.022

Atherosclerosis
Volume 205, Issue 1 , Pages 314-318 , July 2009