Atherosclerosis
Volume 208, Issue 1 , Pages 30-31 , January 2010

A role for MMP-3 genetic variation in atherosclerosis susceptibility?

Received 9 September 2009 ,Accepted 11 September 2009.

References 

  1. Newby AC. Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. Physiol Rev. 2005;85:1–31
  2. Ye S. Influence of matrix metalloproteinase genotype on cardiovascular disease susceptibility and outcome. Cardiovasc Res. 2006;69:636–645
  3. Johnson JL, George SJ, Newby AC, et al. Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries. Proc Natl Acad Sci USA. 2005;102:15575–15580
  4. Silence J, Lupu F, Collen D, et al. Persistence of atherosclerotic plaque but reduced aneurysm formation in mice with stromelysin-1 (MMP-3) gene inactivation. Arterioscler Thromb Vasc Biol. 2001;21:1440–1445
  5. Samnegard A, Silveira A, Lundman P, et al. Serum matrix metalloproteinase-3 concentration is influenced by MMP-3-1612 5A/6A promoter genotype and associated with myocardial infarction. J Intern Med. 2005;258:411–419
  6. Jones GT, Tarr GP, Phillips LV, et al. Active matrix metalloproteinases 3 and 9 are independently associated with coronary artery in-stent restenosis. Atherosclerosis. 2009;
  7. Zhu C, Odeberg J, Hamsten A, et al. Allele-specific MMP-3 transcription under in vivo conditions. Biochem Biophys Res Commun. 2006;348:1150–1156
  8. Ye S, Eriksson P, Hamsten A, et al. Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression. J Biol Chem. 1996;271:13055–13060
  9. Abilleira S, Bevan S, Markus HS. The role of genetic variants of matrix metalloproteinases in coronary and carotid atherosclerosis. J Med Genet. 2006;43:897–901
  10. Koch W, de Waha A, Hoppmann P, et al. Haplotypes and 5A/6A polymorphism of the matrix metalloproteinase-3 gene in coronary disease: case-control study and a meta-analysis. Atherosclerosis. 2010;208:171–176

PII: S0021-9150(09)00732-1

doi: 10.1016/j.atherosclerosis.2009.09.019

Atherosclerosis
Volume 208, Issue 1 , Pages 30-31 , January 2010

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