Atherosclerosis
Volume 212, Issue 2 , Pages 386-387 , October 2010

Hypertriglyceridemia in obese subjects: Caused by reduced apolipoprotein A5 plasma levels?

  • Joerg Heeren

      Affiliations

    • Department of Biochemistry and Molecular Biology II: Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 40 74105 4745; fax: +49 40 74105 4592.
    • ,
  • Martin Merkel

      Affiliations

    • Asklepios Klinik St. Georg, 1. Medizinische Abteilung, Lohmühlenstraße 5, 20099 Hamburg, Germany
    • Tel.: +49 40 18 18 85 2352; fax: +49 40 18 18 85 3029.

Received 8 June 2010 ,Accepted 9 June 2010.

References 

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  13. Talmud PJ, Cooper JA, Hattori H, Miller IP, Miller GJ, Humphries SE. The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: prospective risk of type 2 diabetes Results from the Northwick Park Heart Study II. Diabetologia. 2006;49:2337–2340
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  24. Vu-Dac N, Gervois P, Jakel H, et al. Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators. J Biol Chem. 2003;278:17982–17985
  25. Prieur X, Coste H, Rodriguez JC. The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element. J Biol Chem. 2003;278:25468–25480
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PII: S0021-9150(10)00438-7

doi: 10.1016/j.atherosclerosis.2010.06.020

Atherosclerosis
Volume 212, Issue 2 , Pages 386-387 , October 2010

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