Atherosclerosis
Volume 212, Issue 2 , Pages 656-660 , October 2010

Carotid, aortic arch and coronary calcification are related to history of stroke: The Rotterdam Study

  • Suzette E. Elias-Smale

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Arlette E. Odink

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Renske G. Wieberdink

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Albert Hofman

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Myriam G.M. Hunink

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Gabriel P. Krestin

      Affiliations

    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Peter J. Koudstaal

      Affiliations

    • Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Monique M.B. Breteler

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Aad van der Lugt

      Affiliations

    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Jacqueline C.M. Witteman

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author at: Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands, Tel.: +31 10 7043489; fax: +31 10 7044657.

Received 12 May 2010 ,Revised 18 June 2010 ,Accepted 18 June 2010.

References 

  1. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics – 2010 update. A report from the American Heart Association. Circulation. 2009;
  2. Goldstein LB, Adams R, Alberts MJ, et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006;37:1583–1633
  3. Hollander M, Bots ML, Del Sol AI, et al. Carotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomatic elderly: the Rotterdam study. Circulation. 2002;105:2872–2877
  4. Hunt KJ, Evans GW, Folsom AR, et al. Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study. Stroke. 2001;32:1120–1126
  5. Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation. 2007;115:459–467
  6. Polak JF, Shemanski L, O’Leary DH, et al. Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study. Radiology. 1998;208:649–654
  7. Rundek T, Arif H, Boden-Albala B, et al. Carotid plaque, a subclinical precursor of vascular events: the Northern Manhattan Study. Neurology. 2008;70:1200–1207
  8. Prati P, Tosetto A, Vanuzzo D, et al. Carotid intima media thickness and plaques can predict the occurrence of ischemic cerebrovascular events. Stroke. 2008;39:2470–2476
  9. Amarenco P, Cohen A, Tzourio C, et al. Atherosclerotic disease of the aortic arch and the risk of ischemic stroke. N Engl J Med. 1994;331:1474–1479
  10. Di Tullio MR, Homma S, Jin Z, Sacco RL. Aortic atherosclerosis, hypercoagulability, and stroke the APRIS (Aortic Plaque and Risk of Ischemic Stroke) study. J Am Coll Cardiol. 2008;52:855–861
  11. Jones EF, Kalman JM, Calafiore P, Tonkin AM, Donnan GA. Proximal aortic atheroma. An independent risk factor for cerebral ischemia. Stroke. 1995;26:218–224
  12. Kronzon I, Tunick PA. Aortic atherosclerotic disease and stroke. Circulation. 2006;114:63–75
  13. Culebras A, Otero C, Toledo JR, Rubin BS. Computed tomographic study of cervical carotid calcification. Stroke. 1989;20:1472–1476
  14. Nandalur KR, Baskurt E, Hagspiel KD, et al. Carotid artery calcification on CT may independently predict stroke risk. AJR Am J Roentgenol. 2006;186:547–552
  15. Itani Y, Watanabe S, Masuda Y. Relationship between aortic calcification and stroke in a mass screening program using a mobile helical computed tomography unit. Circ J. 2006;70:733–736
  16. Tanne D, Tenenbaum A, Shemesh J, et al. Calcification of the thoracic aorta by spiral computed tomography among hypertensive patients: associations and risk of ischemic cerebrovascular events. Int J Cardiol. 2007;120:32–37
  17. Vliegenthart R, Hollander M, Breteler MM, et al. Stroke is associated with coronary calcification as detected by electron-beam CT: the Rotterdam Coronary Calcification Study. Stroke. 2002;33:462–465
  18. Folsom AR, Kronmal RA, Detrano RC, et al. Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA). Arch Intern Med. 2008;168:1333–1339
  19. Hofman A, Breteler MM, van Duijn CM, et al. The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol. 2009;24:553–572
  20. Odink AE, van der Lugt A, Hofman A, et al. Risk factors for coronary, aortic arch and carotid calcification; The Rotterdam Study. J Hum Hypertens. 2010;24:86–92
  21. Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  22. Vliegenthart R, Oudkerk M, Hofman A, et al. Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation. 2005;112:572–577
  23. van der Meer IM, Bots ML, Hofman A, et al. Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation. 2004;109:1089–1094
  24. Bots ML, Looman SJ, Koudstaal PJ, et al. Prevalence of stroke in the general population. The Rotterdam Study. Stroke. 1996;27:1499–1501
  25. Iribarren C, Sidney S, Sternfeld B, Browner WS. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. JAMA. 2000;283:2810–2815
  26. Wong ND, Gransar H, Shaw L, et al. Thoracic aortic calcium versus coronary artery calcium for the prediction of coronary heart disease and cardiovascular disease events. JACC Cardiovasc Imaging. 2009;2:319–326
  27. Santos RD, Rumberger JA, Budoff MJ, et al. Thoracic aorta calcification detected by electron beam tomography predicts all-cause mortality. Atherosclerosis. 2010;209:131–135
  28. Rumberger JA, Simons DB, Fitzpatrick LA, Sheedy PF, Schwartz RS. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation. 1995;92:2157–2162
  29. Hyman JB, Epstein FH. A study of the correlation between roentgenographic and post-mortem calcification of the aorta. Am Heart J. 1954;48:540–543
  30. Zureik M, Ducimetiere P, Touboul PJ, et al. Common carotid intima-media thickness predicts occurrence of carotid atherosclerotic plaques: longitudinal results from the Aging Vascular Study (EVA) study. Arterioscler Thromb Vasc Biol. 2000;20:1622–1629
  31. Ioannidis JP, Tzoulaki I. What makes a good predictor?: the evidence applied to coronary artery calcium score. JAMA. 2010;303:1646–1647
  32. Oudkerk M, Stillman AE, Halliburton SS, et al. Coronary artery calcium screening: current status and recommendations from the European Society of Cardiac Radiology and North American Society for Cardiovascular Imaging. Eur Radiol. 2008;18:2785–2807

PII: S0021-9150(10)00493-4

doi: 10.1016/j.atherosclerosis.2010.06.037

Atherosclerosis
Volume 212, Issue 2 , Pages 656-660 , October 2010

Article Tools