Atherosclerosis
Volume 220, Issue 2 , Pages 362-368 , February 2012

Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice

  • Man C. Wong

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • The Dept. of Pulmonology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • Corresponding Author InformationCorresponding author at: Leiden University Medical Center, Department of Pulmonology, Postzone: C3-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Tel.: +31 071 5262082; fax: +31 071 5266927.
  • ,
  • Janna A. van Diepen

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Lihui Hu

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Bruno Guigas

      Affiliations

    • The Dept. of Molecular Cell Biology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Hetty C. de Boer

      Affiliations

    • The Dept. of Nephrology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • The Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Gijs H. van Puijvelde

      Affiliations

    • Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA Leiden, The Netherlands
  • ,
  • Johan Kuiper

      Affiliations

    • Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Gorlaeus Laboratories, P.O. Box 9502, 2300 RA Leiden, The Netherlands
  • ,
  • Anton J. van Zonneveld

      Affiliations

    • The Dept. of Nephrology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • The Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Steven E. Shoelson

      Affiliations

    • Joslin Diabetes Center and the Dept. of Medicine, 1 Joslin Place, Boston, MA 02215, USA
  • ,
  • Peter J. Voshol

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • Present address: Metabolic Research Laboratories, Level 4, Institute of Metabolic Science, Box 289, Addenbrooke's Hospital Cambridge, CB2 0QQ, United Kingdom.
  • ,
  • Johannes A. Romijn

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • Present address: The Dept. of Internal Medicine, University of Amsterdam, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.
  • ,
  • Louis M. Havekes

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • The Dept. of Cardiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • Netherlands Organization for Applied Scientific Research – Biosciences, Gaubius Laboratory, P.O. Box 2215, 2301 CE Leiden, The Netherlands
  • ,
  • Jouke T. Tamsma

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Patrick C.N. Rensen

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Pieter S. Hiemstra

      Affiliations

    • The Dept. of Pulmonology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
  • ,
  • Jimmy F.P. Berbée

      Affiliations

    • The Dept. of General Internal Medicine, Endocrinology, and Metabolic Diseases, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands
    • The Dept. of Experimental Immunohematology, Sanquin Research Amsterdam, P.O. Box 9190, 1006 AD Amsterdam, The Netherlands

Received 30 March 2011 ,Revised 3 June 2011 ,Accepted 29 June 2011.

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PII: S0021-9150(11)00578-8

doi: 10.1016/j.atherosclerosis.2011.06.055

Atherosclerosis
Volume 220, Issue 2 , Pages 362-368 , February 2012