Atherosclerosis
Volume 220, Issue 2 , Pages 449-455 , February 2012

Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

  • Ada Congrains

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Kei Kamide

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Ryousuke Oguro

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Osamu Yasuda

      Affiliations

    • Department of Cardiovascular Clinical and Translational Research, Kumamoto University Hospital, Japan
    • ,
  • Keishi Miyata

      Affiliations

    • Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Japan
    • Immunology, Allergy and Vascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Japan
    • ,
  • Eiichiro Yamamoto

      Affiliations

    • Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Japan
    • ,
  • Tatsuo Kawai

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Hiroshi Kusunoki

      Affiliations

    • Clinical Gene Therapy, Osaka University Graduate School of Medicine, Japan
    • ,
  • Hiroko Yamamoto

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Yasushi Takeya

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Koichi Yamamoto

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Miyuki Onishi

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Ken Sugimoto

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • ,
  • Tomohiro Katsuya

      Affiliations

    • Clinical Gene Therapy, Osaka University Graduate School of Medicine, Japan
    • ,
  • Nobuhisa Awata

      Affiliations

    • Department of Cardiology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
    • ,
  • Kazunori Ikebe

      Affiliations

    • Department of Prosthodontics and Oral Rehabilitation, Osaka University Graduate School of Dentistry, Japan
    • ,
  • Yasuyuki Gondo

      Affiliations

    • Department of Clinical Thanatology and Geriatric Behavioral Science, Osaka University, Graduate School of Human Sciences, Japan
    • ,
  • Yuichi Oike

      Affiliations

    • Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Japan
    • ,
  • Mitsuru Ohishi

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan
    • Corresponding Author InformationCorresponding author at: Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka (B6), Suita, Osaka 565-0871, Japan. Tel.: +81 6 6879 3852; fax: +81 6 6879 3859.
    • ,
  • Hiromi Rakugi

      Affiliations

    • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan

Received 13 September 2011 ,Revised 31 October 2011 ,Accepted 11 November 2011.

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☆ This study was supported in part by grants-in-aid from the Program for Promotion of Fundamental Studies in National Institute of Biomedical Innovation of Japan (HR: 22-2-5), the Ministry of Education, Culture, Sports, Science, and Technology of Japan (KK: 22510211) and NOVARTIS Foundation for Gerontological Research (KK).

PII: S0021-9150(11)01086-0

doi: 10.1016/j.atherosclerosis.2011.11.017

Atherosclerosis
Volume 220, Issue 2 , Pages 449-455 , February 2012

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