Atherosclerosis
Volume 146, Issue 1 , Pages 117-124 , September 1999

The effects of dyslipidemia on left ventricular systolic function in patients with stable angina pectoris

  • Tzung-Dau Wang

      Affiliations

    • Section of Cardiology, Department of Internal Medicine, En Chu Kong Hospital, Taipei Hsien, Taiwan, ROC
    • Corresponding Author InformationCorresponding author. Present address: Department of Internal Medicine (Cardiology), National Taiwan University Hospital, 7, Chung-Shan South Rd., Taipei, 10016, Taiwan, ROC. Tel.: +886-2-2356-2152; fax: +886-2-2643-3511
  • ,
  • Chii-Ming Lee

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Chau-Chung Wu

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Tsung-Ming Lee

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Wen-Jone Chen

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Ming-Fong Chen

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Chiau-Suong Liau

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC
  • ,
  • Fung-Chang Sung

      Affiliations

    • College of Public Health, National Taiwan University, Taipei, Taiwan, ROC
  • ,
  • Yuan-Teh Lee

      Affiliations

    • Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan, ROC

Received 1 January 1999 ,Revised 22 February 1999 ,Accepted 9 March 1999.

References 

  1. Scandinavian Simvastatin Survival Study Group. Randomized trial of cholesterol lowering therapy in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994;344:1383–1389.
  2. Shepherd J, Cobbe SM, Isles CG, Lorimer AR, MacFarlane PN, Mckillop JH, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. The West of Scotland Coronary Prevention Study Group. New Engl J Med. 1995;333:1301–1307
  3. Jenkins GH, Grieve LA, Yacoub MH, Singer DRJ. Effect of Simvastatin on ejection fraction in cardiac transplant recipients. Am J Cardiol. 1996;78:1453–1456
  4. Lars Bastiaanse EM, Atsma DE, Kuijpers MMC, Van der Laarse A. The effect of sarcolemmal cholesterol content on intracellular calcium ion concentration in cultured cardiomyocytes. Arch Biochem Biophys. 1994;313:58–63
  5. Liu K, Massaeli H, Pierce GN. The action of oxidized low-density lipoprotein on calcium transients in isolated rabbit cardiomyocytes. J Biol Chem. 1993;268:4145–4151
  6. Wang TD, Wu CC, Chen WJ, Lee CM, Chen MF, Liau CS, et al. Dyslipidemias have a detrimental effect on left ventricular systolic function in patients with a first myocardial infarction. Am J Cardiol. 1998;81:531–537
  7. Kempen HJ, Van Gent CM, Buytenhek R, Buis B. Association of cholesterol concentrations in low-density lipoprotein, high-density lipoprotein, and high-density lipoprotein subfractions, and of apolipoproteins AI and AII, with coronary stenosis and left ventricular function. J Lab Clin Med. 1987;109:19–26
  8. National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1983;28:1039–1057.
  9. Allain LA, Poon LS, Chan LSG, Richmond W, Fu PL. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470–475
  10. McGowan MW, Artiss JD, Strandbergh DR, Zak B. A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin Chem. 1983;29:538–542
  11. Buege JA, Aust SD. Microsomal lipid peroxidation methods. Enzymology. 1978;52:302
  12. Rifani N, Silverman LM. A simple immunotechnique for the determination of serum concentration of apolipoprotein E. Clin Chim Acta. 1987;163:207–213
  13. Fless GM, Snyer ML, Scanu AM. Enzyme-linked immunoassay for Lipoprotein (a). J Lipid Res. 1989;30:651–652
  14. Judkins MP. Selective coronary arteriography, part I: a percutaneous transfemoral approach. Radiology. 1967;89:815–819
  15. Gensini G. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 1983;51:606
  16. Lauer MS, Evans JC, Levy D. Prognostic implications of subclinical left ventricular dilatation and systolic dysfunction in men free of overt cardiovascular disease (the Framingham Heart Study). Am J Cardiol. 1992;70:1180–1184
  17. Ross J. Myocardial perfusion-contraction matching: implications for coronary heart disease and hibernation. Circulation. 1991;83:1076–1083
  18. Lewis SJ, Sawada SG, Ryan T, Segar DS, Armstrong WF, Feigenbaum H. Segmental wall motion abnormalities in the absence of clinically documented myocardial infarction: clinical significance and evidence of hibernating myocardium. Am Heart J. 1991;121:1088–1094
  19. Ragosta M, Beller GA, Watson DD, Kaul S, Gimple LW. Quantitative planar rest-redistribution 201 Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function. Circulation. 1993;87:1630–1641
  20. National Cholesterol Education Program. Second report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel II). Circulation 1994;89:1333–1445.
  21. Grundy SM, Goodman DS, Rifkind BM. The place of HDL in cholesterol management: A perspective from the National Cholesterol Education Program. Arch Intern Med. 1989;149:505–510
  22. Lien WP, Lai LP, Shyu KG, Hwang JJ, Chen JJ, Lei MH, et al. Low-serum high-density lipoprotein cholesterol concentration is an important coronary risk factor in Chinese patients with low serum levels of total cholesterol and triglyceride. Am J Cardiol. 1996;77:1112–1115
  23. Chen Z, Peto R, Collins R, MacMahon S, Lu J, Li W. Serum cholesterol concentration and coronary heart disease in population with low cholesterol concentrations. Br Med J. 1991;303:276–282
  24. Cannon RO, Epstein SE. Microvascular angina as a cause of chest pain with angiographically normal coronary arteries. Am J Cardiol. 1988;61:1338–1343
  25. Motz W, Wogt M, Rabenan O, Scheler S, Luckhoff A, Strauer BE. Evidence of endothelial dysfunction in coronary resistance vessels in patients with angina pectoris and normal coronary angiograms. Am J Cardiol. 1991;68:996–1003
  26. Egashira K, Inou T, Hirooka Y, Yamada A, Urabe Y, Takeshita A. Evidence of impaired endothelium-dependent coronary vasodilatation in patients with angina pectoris and normal coronary angiograms. New Engl J Med. 1993;328:1659–1664
  27. Hessler JR, Robertson AL, Chisolm GM. LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture. Atherosclerosis. 1979;32:213–219
  28. Matsuda Y, Hirata KI, Inoue N, Suematsu M, Kawashima S, Akita H, et al.  High density lipoprotein reverses inhibitory effect of oxidized low density lipoprotein on endothelium-dependent arterial relaxation. Circ Res. 1993;72:1103–1109
  29. Reaven GM. Role of insulin resistance in human disease (syndrome X): An expanded definition. Annu Rev Med. 1993;44:121–131
  30. Steinberg HO, Brechtel G, Johnson A. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. J Clin Invest. 1994;94:1172–1179
  31. Chauhan A, Foote J, Petch MC, Schofield PM. Hyperinsulinemia, coronary artery disease and syndrome X. J Am Coll Cardiol. 1994;23:364–368
  32. Stimpel M, Neyses L, Locher R, Knorr M, Vetter W. High-density lipoprotein—modulators of the calcium channel?. J Hypertens. 1986;3(Suppl 3):49–51
  33. Mintz GS, Painter JA, Pichard AD, Kent KM, Satler LF, Popma JJ, et al. Atherosclerosis in angiographically normal coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol. 1995;25:1479–1485
  34. Zarich SW, Nesto RW. Diabetic cardiomyopathy. Am Heart J. 1989;118:1000–1012
  35. Pollare T, Lithell H, Selinus I, Berne C. Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double-blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. Br Med J. 1989;298:1152–1157
  36. Keil U, Kuulasmaa K. The WHO MONICA project: risk factors. Int J Epidemiol. 1989;18(Suppl 1):46–55

PII: S0021-9150(99)00108-2

Atherosclerosis
Volume 146, Issue 1 , Pages 117-124 , September 1999