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Atherosclerosis
Volume 146, Issue 1
, Pages 133-140
, September 1999
Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population
References
- . The pathogenesis of coronary artery disease: a possible role for methionine metabolism. J Clin Invest. 1976;57:1079–1082
- . Disordered methionine/homocysteine metabolism in premature vascular disease: its occurrence, cofactor therapy and enzymology. Arterioscler Thromb. 1993;13:1253–1260
- . Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med. 1991;324:1149–1155
- . Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med. 1995;332:286–291
-
.
Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease.
New Engl J Med. 1985;313:709–715
- Plasma homocysteine as a risk factor for vascular disease. The European concerted action project. JAMA. 1997;277:1775–1781
-
.
Plasma homocysteine levels and mortality in patients with coronary artery disease.
New Engl J Med. 1997;337:230–236
- . Is hyperhomocysteinaemia a risk factor for recurrent venous thrombosis?. Lancet. 1995;345:882–885
-
.
Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide.
Europ J Clin Invest. 1979;9:301–307
-
.
Homocysteine in the plasma of renal transplant recipients: effects of cofactors for methionine metabolism.
Clin Sci. 1981;61:743–749
- . Folic acid lowers elevated plasma homocyst(e)ine in chronic renal insufficiency: possible implications for prevention of vascular disease. Metabolism. 1988;37:697–701
- . Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations. Circulation. 1996;94:2743–2748
-
.
Mechanisms of thrombogenesis and accelerated atherogenesis in homocysteinaemia.
Haemostasis. 1989;19:14–23(supp. 1)
- . The role of free radicals as mediators of endothelial cell injury in hyperhomocysteinemia. Ir J Med Sci. 1992;161:561–564
-
.
Characterization of the stress-inducing effects of homocysteine.
Biochem J. 1998;332:213–221
-
.
Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis.
Proc Natl Acad Sci USA. 1994;91:6369–6373
- . Homocysteine signal cascade: production of phospholipids, activation of protein kinase C, and the induction of c-fos and c-myb in smooth muscle cells. FASEB J. 1997;11:703–711
-
Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D, editors. The Metabolic Basis of Inherited Disease, 6th Edn. New York: McGraw-Hill, 1995: 1279–1326.
- . Metabolism of homocysteine thiolactone in human cell cultures. J Biol Chem. 1997;272:1935–1942
- . Linkage mapping of the cystathionine β-synthase (CBS) gene on human chromosome 21 using a DNA polymorphism in the 3′ untranslated region. Hum Genet. 1993;90:566–568
- . Human methionine synthase. cDNA cloning, gene localization, and expression. J Biol Chem. 1997;272:3628–3634
-
.
Disorders of homocysteine metabolism.
J Inher Metab Dis. 1997;20:270–285
- . Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Genet. 1994;7:195–200
-
.
Screening for mutations by expressing patient cDNA segments in E. coli: homocystinuria due to cystathionine β-synthase deficiency.
Hum Mut. 1992;1(2):113–123
- . Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency. Am J Hum Genet. 1995;56:1052–1059
- . Molecular basis of cystathionine beta-synthase deficiency in pyridoxine responsive and nonresponsive homocystinuria. Hum Mol Genet. 1993;2(11):1857–1860
-
.
Molecular basis of phenotype expression in homocystinuria.
J Inher Metab Dis. 1994;17:383–390
- . A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10:111–113
- . Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 1993;88:1463–1469
- . Common mutation in methylenentetrahydrofolate reductase. correlation with homocysteine metabolism and late-onset vascular disease. Circulation. 1996;94:3074–3078
- . Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease—the results of a meta analysis. Circulation. 1998;98:2520–2526
- . Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation. 1996;94:2410–2416
- . Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation. Arterioscler Thromb Vasc Biol. 1996;16:878–882
- . A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among US men. J Am Coll Cardiol. 1998;32:353–359
- . Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine and coronary disease. Circulation. 1997;96:2738–2739
- . High prevalence of a mutation in the cystathionine β-synthase gene. Am J Hum Genet. 1996;59:1262–1267
- . Human methionine synthase: cDNA cloning and identification of mutations in patients of cbIG complementation group of folate/cobalamin disorders. Hum Mol Genet. 1996;5:1867–1874
- . Defects in human methionine synthase in cbiG patients. Hum Mol Genet. 1996;5:1859–1865
- . Determinants of severity of coronary artery disease in Australian men and women. Circulation. 1994;89:1974–1981
- . Quantitative analysis of extracellular-superoxide dismutase in serum and urine by ELISA with monoclonal antibody. Clin Chim Acta. 1992;212:89–102
- . Plasma extracellular superoxide dismutase levels in an Australian population with coronary artery disease. Arterioscler Thromb Vasc Biol. 1998;18:1915–1921
-
.
The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase.
Arterioscler Thromb Vasc Biol. 1995;15:2031–2036
- . Extracellular superoxide dismutase in the vascular system of mammals. Biochem J. 1988;255:223–228
-
.
Heparin-affinity patterns and composition of extracellular-superoxide dismutase in human plasma and tissues.
Biochem J. 1993;294:847–853
- . Pharmacokinetics of extracellular-superoxide dismutase in the vascular system. Free Radic Biol Med. 1993;14:185–190
- . Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins. The atherosclerosis risk in communities (ARIC) study. Circulation. 1998;98:204–210
- . Homocysteine, vitamins, and cardiovascular disease. Circulation. 1998;98:196–199
-
.
The frequency of a common mutation of the methionine synthase gene in the Australian population and its relation to coronary artery disease.
J Cardiovascular Risk. 1998;5:289–295
PII: S0021-9150(99)00111-2
© 1999 Elsevier Science Ireland Ltd. All rights reserved.
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Atherosclerosis
Volume 146, Issue 1
, Pages 133-140
, September 1999
