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Distribution of alkanes in normal and atherosclerotic rabbit aortas

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      Abstract

      Hydrocarbon fractions were isolated from lipid extracts of normal and atherosclerotic rabbit aortas. They were analyzed by thin-layer chromatography and gas-liquid chromatography. The principal constituents in both normal and atherosclerotic tissue consisted of a homologous series of n-alkanes (C18C34). Also detected were homologous series of iso and anteiso-alkanes, dimethyl branched alkanes and squalene.
      Although the hydrocarbon composition of both normal and sclerotic aortas is essentially the same, the amount and proportion of each hydrocarbon varied.

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