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Abstract
Atherosclerosis was induced in cynomolgus monkeys (Macaca iya) fed on a semipurified diet containing 0.5% cholesterol. No differences in the extent
of aortic or coronary atherosclerosis were observed when pyridinolcarbamate (2–6 pyridine-dimethanol-bis
(N-methylcarbamate)), was added to the diet at concentrations ranging from 400–2000
mg/kg food.
Keywords
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References
- Occlusive atherosclerotic disease of the coronary arteries in monkey (Macaca irus) induced by diet.Exp. Molec. Pathol. 1968; 9: 1
- The effects of pyridinolcarbamate on induced atherosclerosis in monkeys.J. Atheroscler. Res. 1968; 8: 455
- The effect of pyridinolcarbamate on the induction and regression of aortic and coronary atherosclerosis in cholesterol-fed cockerels.in: Shimamoto T. Numano F. Atherogenesis. Excerpta Medica, Amsterdam1969: 57
- Pyridinolcarbamate, a bradykinin antagonist in veins.Amer. Heart J. 1966; 71: 297
- Atherosclerosis-inhibiting effect of an antibradykinin agent, pyridinolcarbamate.Amer. Heart J. 1966; 71: 216
- A study of the anti-inflammatory action of pyridinolcarbamate (Anginin).in: Shimamoto T. Numano F. Atherogenesis. Excerpta Medica, Amsterdam1969: 133
- New method for direct determination of serum cholesterol.J. Lab. Clin. Med. 1953; 41: 486
Article info
Publication history
Received:
March 31,
1971
Footnotes
☆Publication No. 524 of the Oregon Regional Primate Research Center. This study was supported by Grant FR-00163 of the National Institutes of Health, the Japanese Institute for Cardiovascular Diseases and the pyridinolcarbamate was a gift from the Banyu Pharmaceutical Co., Ltd., Tokyo, Japan.
Identification
Copyright
© 1971 Published by Elsevier Inc.
