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Abstract
The influence of feeding spinach or wakame on the turnover of cholesterol was studied
in rats with a high plasma cholesterol level. The half-lives of cholesterol were estimated
by measuring the faecal excretion of [3H] cholesterol injected intraperitoneally, and were found to be 28.2, 15.2 and 20.5
days, respectively, for rats fed the control sucrose diet, that supplemented with
5% spinach powder and that supplemented with 5% wakame powder. It is suggested from
the analysis of faecal cholesterol metabolites that spinach stimulated the intestinal
microflora to form more coprostanol from cholesterol, while wakame suppressed the
reabsorption of cholesterol in the enterohepatic circulation.
Keywords
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References
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Article info
Publication history
Received:
June 24,
1971
Identification
Copyright
© 1971 Published by Elsevier Inc.