Cholesterol vehicle in experimental atherosclerosis

Part 12. Rapeseed oil
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      Rabbits were fed diets containing 2% cholesterol and 6% of either rapeseed oil (RSO) or corn oil (CO). In three experiments there were no differences in atherogenicity of the two oils. Serum cholesterol and liver triglyceride levels were similar in the two groups, whereas serum triglycerides and liver cholesterols were somewhat lower in rabbits fed cholesterol and RSO. From gas chromatographic analysis of the triglycerides and cholesterol esters of aortas and livers, there is indirect evidence for the conversion of erucic to oleic acid. At the level and time period of feeding (6%, 2 months) RSO did not exert a deleterious effect on the rabbits.


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