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Research paper| Volume 15, ISSUE 2, P153-162, March 01, 1972

Muscular activity and the degradation of cholesterol by the liver

  • M.R. Malinow
    Affiliations
    Department of Cardiovascular Physiology, Oregon Regional Primate Research Center, Beaverton, Oreg., 97005, USA

    University of Oregon Medical School, Portland, Oreg. U.S.A.
    Search for articles by this author
  • Phyllis McLaughlin
    Affiliations
    Department of Cardiovascular Physiology, Oregon Regional Primate Research Center, Beaverton, Oreg., 97005, USA

    University of Oregon Medical School, Portland, Oreg. U.S.A.
    Search for articles by this author
  • Irene Pierovich
    Affiliations
    Department of Cardiovascular Physiology, Oregon Regional Primate Research Center, Beaverton, Oreg., 97005, USA

    University of Oregon Medical School, Portland, Oreg. U.S.A.
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DOI:https://doi.org/10.1016/0021-9150(72)90065-2
Muscular activity and the degradation of cholesterol by the liver
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      Abstract

      [1, 2 α-3H]Cholesterol lipoproteins were injected intravenously into bile-duct cannulated anesthetized rats; cholic [14C]carboxyl acid or radiopaque material was introduced into the small intestine. The animals also received intraenteric infusions of bile with or without whipping cream. Repeated contractions of the skeletal musculature increased the biliary secretion of products from the cyclic portion of the cholesterol molecule and of absorbed [14C]cholic acid without modifying intestinal motility.

      Keywords

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      Article Info

      Publication History

      Received: July 2, 1971

      Footnotes

      ☆Publication No. 562 of the Oregon Regional Primate Research Center. Aided by the National Institutes of Health Grant FR 00163, by the John C. Higgins Memorial Fund, and Grant No. HE 12694-02 of the National Heart Institute.

      Identification

      DOI: https://doi.org/10.1016/0021-9150(72)90065-2

      Copyright

      © 1972 Published by Elsevier Inc.

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