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Research paper| Volume 15, ISSUE 2, P223-230, March 1972

Hypolipidaemic activity of Phaseolus mungo (blackgram) in rats fed a high-fat-high-cholesterol diet

Isolation of a protein and polysaccharide fraction
DOI:https://doi.org/10.1016/0021-9150(72)90072-X
Hypolipidaemic activity of Phaseolus mungo (blackgram) in rats fed a high-fat-high-cholesterol diet
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      Abstract

      Blackgram (Phaseolus mango) has been previously reported to have a pronounced hypolipidaemic action in rats fed a hypercholesterolaemic diet. A protein and an insoluble polysaccharide fraction have now been isolated which decrease the level of total cholesterol and phospholipid in the serum, liver and aorta in rats fed a high-fat-high-cholesterol diet. The fatty acids isolated from the lipid fractions also have some hypolipidaemic effect, though to a lesser extent. The protein fraction has the solubility characteristics of a globulin and contains a carbohydrate residue. The polysaccharide fraction contains 3.36% N.

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      Article info

      Publication history

      Received: August 16, 1971

      Footnotes

      ☆Patent application has been filed for patent rights for the isolation of these fractions.

      Identification

      DOI: https://doi.org/10.1016/0021-9150(72)90072-X

      Copyright

      © 1972 Published by Elsevier Inc.

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