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Abstract
After development of an experimentally induced renal hypertension in rats, elevated
concentrations of cholesterol and phospholipids in serum were observed. The additional
ligature of the thoracic duct in normotensive and hypertensive animals further increased
the lipid content of serum in hypertensive rats and promoted an even more severe hyperlipaemia
in normotensive animals. In both experimental groups the hyperlipaemia took a biphasic
course. The lipids measured approached their intitial values on the 15th day following
the ligature of the ductus thoracicus. Moreover the ligature of the thoracic duct
modified the total lipid content of the liver and induced pronounced morphological
alterations of liver tissue.
Keywords
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References
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Article info
Publication history
Received in revised form:
November 20,
1972
Footnotes
☆This investigation was supported in part (H.C.) by the Deutsche Forschungsgemeinschaft.
Identification
Copyright
© 1973 Published by Elsevier Inc.
