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Abstract
The effect of oral administration of varying doses of a polysaccharide fraction isolated
from bran and husk of paddy on the cholesterol, phospholipid and triglyceride levels
of the serum, liver and aorta in rats fed a high-fat-high-cholesterol diet has been
studied. At a daily dose of 15 mg per rat per day, these levels were comparable to
those in rats fed a normal diet. The substance, while having no appreciable effect
on cholesterol absorption, considerably increased the breakdown of cholesterol to
bile salts and caused increased faecal bile salt excretion. The polysaccharide fraction
contains 41.53% carbohydrate, 7.48% uronic acid, 0.54% hexosamine, 22.03 proteins,
1.78 % sulphate and 4.3 % acetyl groups. It is found to contain two components one
precipitable by cetylpyridinium chloride (42%) and the other not precipitable (58%).
Keywords
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References
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Article info
Publication history
Received in revised form:
November 21,
1972
Identification
Copyright
© 1973 Published by Elsevier Inc.
