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Abstract
The globulin fraction from blackgram at the 5 % dose level kept the cholesterol, phospholipid
and triglyceride levels of the serum, liver and aorta of rats fed a highfat- high-cholesterol
level at much the same level as in rats fed a normal diet. The polysaccharide fraction
at the 56% dose level showed a similar lipid-lowering effect. Thus, the protein fraction
seemed to be more effective in decreasing the total cholesterol and triglyceride levels
than the polysaccharide fraction.
Although the globulin fraction increased cholesterol absorption from the intestine,
it also increased the breakdown of cholesterol to bile salts and caused increased
faecal excretion of bile salts. The polysaccharide fraction increased excretion of
both faecal sterols and bile salts.
The globulin fraction contains a carbohydrate residue and is heterogeneous on acrylamide
gel electrophoresis. The polysaccharide fraction contains glucose, galactose, mannose,
small amounts of hexosamines, and appreciable quantities of uronic acids, sulphate
and acetyl groups. It also contains about 20% alkali-extractable protein and about
7.3% fibre.
Keywords
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References
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Article info
Publication history
Received in revised form:
November 21,
1972
Identification
Copyright
© 1973 Published by Elsevier Inc.
