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Abstract
Turkeys injected with a single dose of diethylstilbestrol (DES) (15, 30 or 60 mg)
develop a hyperlipoproteinemia which is characterized by a large increase in chylomicrons,
a weak pre-beta lipoprotein concentration and an absence of beta- and alpha-lipoproteins.
The hyperlipoproteinemia was pronounced between 3 and 12 days post injection. The
rate and degree of development of the induced hyperlipoproteinemia is similar for
the 3 levels of DES injected. Increased concentrations of cholesterol and protein
are found in the low-density lipoproteins (LDL) between 4 and 20 days post injection,
while the cholesterol and protein content of the high-density lipoproteins (HDL) are
greatly reduced. The levels of cholesterol and protein in the LDL HDL HDL return to
normal on day 44 post injection.
Keywords
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References
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Article info
Publication history
Received in revised form:
December 19,
1972
Identification
Copyright
© 1973 Published by Elsevier Inc.
