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Serum cholesterol esterification in species resistant and susceptible to atherosclerosis

  • Andras G. Lacko
    Affiliations
    Lipid Research Laboratory, Section of Cardiology, Department of Medicine and the Fels Research Institute, Temple University Health Sciences Center, 3401 North Broad Street, Philadelphia, Penna. 19140 U.S.A.
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  • Harold L. Rutenberg
    Affiliations
    Lipid Research Laboratory, Section of Cardiology, Department of Medicine and the Fels Research Institute, Temple University Health Sciences Center, 3401 North Broad Street, Philadelphia, Penna. 19140 U.S.A.
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  • Louis A. Soloff
    Affiliations
    Lipid Research Laboratory, Section of Cardiology, Department of Medicine and the Fels Research Institute, Temple University Health Sciences Center, 3401 North Broad Street, Philadelphia, Penna. 19140 U.S.A.
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      Abstract

      Initial rates of cholesterol esterification were measured in rat, rabbit, pig, dog, guinea pig and human serum. The data indicate a tendency for the rate of esterification to increase with serum free cholesterol levels in all species.
      The fractional rate of esterification ( % cholesterol esterified/min) for the species in decreasing order are rat, guinea pig, rabbit, dog, pig and man.

      Keywords

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