Further studies on serum lipoproteins in connective tissue diseases

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      Men with ankylosing spondylitis (AS) and females with systemic lupus erythematosus (SLE) were found to have low total serum lipid concentrations similar to results previously obtained in patients with rheumatoid arthritis (RA). In AS men total serum TG was about 50% of control values and in AS men and SLE women total serum cholesterol was 78% of control values but close to corresponding RA concentrations. This was explained mainly by low LDL concentrations. There was a marked difference between RA patients and AS and SLE patients in that the two latter groups had normal HDL cholesterol concentrations whereas in RA patients the HDL cholesterol concentration was only 70% of control values.
      Thus in spite of similar and low total serum lipid concentrations, differences in lipoprotein composition were found in the three different rheumatic diseases, underlining the importance of lipoprotein analyses in the study of dyslipoproteinaemia.


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        • Rössner S.
        • Löfmark C.
        Dyslipoproteinaemia in patients with active, chronic polyarthritis — A study on serum lipoproteins and triglycerides clearance (Intravenous Fat Tolerance Test).
        Atherosclerosis. 1977; 28: 41-52
        • Carlson K.
        Lipoprotein fractionation.
        J. Clin. Path. Suppl. (Ass. Clin. Path.). 1973; 5: 32
        • Kessler G.
        • Lederer H.
        Fluorimetric measurement of triglycerides.
        in: Automation in Analytical Chemistry. Vol. 1. Medical Books Inc, New York, NY1965: 341
        • Block W.D.
        • Jarrett K.J.
        • Leoine B.
        Use of a single color reagent to improve the automated determination of serum total cholesterol.
        in: Automation in Analytical Chemistry. Vol. 1. Medical Books, Inc, New York, NY1965: 345
        • Carlson L.A.
        • Ericsson M.
        Quantitative and qualitative serum lipoprotein analysis, Part 1 (Studies in healthy men and women).
        Atherosclerosis. 1975; 21: 417
        • Koota K.
        • Isomäki H.
        • Mutru O.
        Death rate and causes of death in RA patients during a period of five years.
        Scand. J. Rheumatol. 1977; 6: 241-244
        • Haataja M.
        Evaluation of the activity of rheumatoid arthritis.
        Sci. J. Rheumatol. 1976; 4
        • Gerasimova Ye.M.
        • Perova N.V.
        • Speranskaya I.A.
        • Karmansky I.M.
        The effect of glucocorticoids on transformation of plasma lipoproteins in experimental atherosclerosis.
        Vopr. Med. Chim. 1974; 20: 418-424
        • Mjøs O.
        High density lipoprotein and coronary heart disease (Editorial).
        Scand. J. Clin. Lab. Invest. 1977; 37: 191-193
        • Olsson A.G.
        Studies in asymptomatic primary hyperlipidaemia — Clinical, biochemical and physiological investigations.
        Acta Med. Scand., Suppl. 1975; 581
        • Johansson C.
        • Rössner S.
        • Walldius G.
        HDL secretion from human intestinal tract (Letter).
        Lancet. 11 February 1978; : 324-325
        • Rössner S.
        • Johansson C.
        • Walldius G.
        • Aly A.
        Intralipid clearance in men with alcoholic liver cirrhosis.
        Amer. J. Clin. Nutr. 1978; (Submitted to)
        • Olhagen B.
        On the aetiopathogenesis of rheumatoid arthritis.
        Ann. Clin. Res. 1975; 7: 119-128
        • Olhagen B.
        • Månsson I.
        Intestinal clostridium perfringens in rheumatoid arthritis and other collagen diseases.
        Acta Med. Scand. 1968; 184: 395-402