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Research paper| Volume 42, ISSUE 2-3, P197-203, April 1982

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Discriminative value of lipids and apoproteins in coronary heart disease

DOI:https://doi.org/10.1016/0021-9150(82)90150-2
Discriminative value of lipids and apoproteins in coronary heart disease
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      Abstract

      Serum cholesterol, HDL cholesterol (HDL-C), and apoproteins, A1, A2 and B were determined in 70 male survivors of myocardial infarction and in an equal number of healthy controls, matched for age, sex and body mass index. In univariate analyses, the Apo B/Apo A1 ratio discriminated the best between cases and controls, giving a 72% exact classification. In a multivariate analysis, the Apo B/Apo A1 ratio, HDL-C and the Apo A2/Apo A1 ratio contributed independently to the discrimination of cases from controls while the overall exact classification was 82%. These promising results were comparable in younger and older subgroups.
      Thus, the determination of apoproteins yielded complementary information in this cross-sectional survey and warrants further study in a prospective setting.

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      Article info

      Publication history

      Accepted: September 14, 1981
      Received: August 7, 1981

      Identification

      DOI: https://doi.org/10.1016/0021-9150(82)90150-2

      Copyright

      © 1982 Published by Elsevier Inc.

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