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Abstract
Cessation of smoking is followed by a rapid rise in plasma HDL concentrations. An
earlier study has demonstrated a significant relationship between the increase in
HDL concentrations and spontaneous changes in food intake, specifically an increased
fat intake. In this investigation we have dissociated the effects of cessation of
smoking as such from those of dietary alterations by monitoring plasma lipid and lipoprotein
concentrations after cessation of smoking in 12 subjects whose diet was kept constant
during an initial 2-week control period and during 2 weeks following cessation of
smoking. Under these conditions plasma HDL-cholesterol levels did not increase significantly
(1.01 ± 0.26 mmol/1 (mean ± SD) before and 1.04 ± 0.27 mmol/1 after cessation of smoking).
Similarly, no significant alterations were recorded for other plasma lipid or lipoprotein
concentrations. Activities of lipoprotein lipase and hepatic lipase were unchanged
throughout the study. These results suggest that the marked rise in HDL concentrations
after stopping smoking is largely related to spontaneous changes in dietary habits
which occur upon cessation of smoking.
Keywords
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Article info
Publication history
Accepted:
October 14,
1988
Received in revised form:
September 15,
1988
Received:
March 25,
1988
Identification
Copyright
© 1989 Published by Elsevier Inc.