Lipids, lipoproteins, apolipoproteins, and other risk factors in Chinese men and women with and without myocardial infarction

      This paper is only available as a PDF. To read, Please Download here.


      One hundred and fifty-four male and 69 female Chinese patients, aged between 40 and 60 years, who had suffered myocardial infarction (Ml) were investigated and compared with 216 men and 219 women who had no history or ECG evidence of coronary heart disease. The male MI patients had significantly raised levels of triglycerides (160 mg/dl), cholesterol (194 mg/dl), VLDL-CH (31 mg/dl), apolipoprotein B (122 mg/dl) and apolipoprotein E (4.7 mg/dl) and a lower apolipoprotein A-I level (126 mg/dl) than the control group (triglycerides 131, cholesterol 179, VLDL-CH 26, apo B 102, apo E4.2, and apo A-I 138 mg/dl). The women with MI also had higher values for the atherogenic lipids than the control group (triglycerides 175 vs. 134 mg/dl, cholesterol 218 vs. 186 mg/dl, LDL-CH 128 vs. 104 mg/dl, VLDL-CH 32 vs. 26 mg/dl, apo B 121 vs. 103 mg/dl and apo E 5.4 vs. 4.3 mg/dl), as well as lowered apolipoprotein A-I (128 vs. 144 mg/dl). The Lp(a) levels (men and women considered together) were significantly higher for the MI patients (34.3 mg/dl vs. 26.2 mg/dl). Anti-atherogenic lipoproteins such as HDL-cholesterol, HDL2-CH, HDL3-CH, phospholipids and apolipoprotein A-II, C-II and C-III showed no difference between the groups.



      apo (apolipoprotein), BMI (body mass index), CHD (coronary heart disease), MI (myocardial infarction), TG (triglycerides), CH (cholesterol)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Atherosclerosis
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Luo C.I.
        • Lui M.
        • Ping Y.
        • Gou Z.
        Blood lipid analysis in coronary heart disease and significance.
        Tianjin Med. Med. J. 1986; 1: 10
        • Kesteloot H.
        • Huang D.X.
        • Yang X.S.
        • Claes J.
        • Rosseneu M.
        • Geboers J.
        • Joossens J.V.
        Serum lipids in the People's Republic of China. Comparison of Western and Eastern populations.
        Arteriosclerosis. 1985; 5: 427
        • Bernhardt R.
        • Feng Z.
        • Deng Y.
        • Wang Z.
        • Zeng J.
        • Cheng S.
        • Cremer P.
        • Thiery J.
        • Seidel D.
        • Schettler G.
        Coronary risk factors in China: a comparative study of middle-aged workers in China and Germany.
        in: Stehle G. Bernhardt R. Coronary Risk Factors in Japan and China. Springer-Verlag, Berlin-Heidelberg-New York1987: 22
        • Stehle G.
        • Hinohara S.
        • Tamachi H.
        • Kanemoto N.
        • Takahashi T.
        • Gross K.
        • Arab L.
        • Schettler G.
        • Goto Y.
        Blood lipid patterns of healthy Japanese population.
        in: Stehle G. Bernhardt R. Coronary Risk Factors in Japan and China. Springer-Verlag, Berlin-Heidelberg-New York1987: 1
        • Publication of the Tianjin Sanitary and Disease Prevention Center
        Mortality in the Tianjin area.
        in: 1984: 2 (Tianjin)
        • Statistisches Bundesamt Wiesbaden
        Statistisches Jahrbuch 1983 fur die Bundesrepublik Deutschland.
        Kohlhammer, Stuttgart1984
        • Trinder P.
        Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor.
        Ann. Clin. Biochem. 1969; 6: 24
        • Siedel J.
        • Hägele E.O.
        • Ziegenhorn J.
        • Wahlefeld A.W.
        Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficacy.
        Clin. Chem. 1983; 29: 1075
        • Kattermann R.
        Multicenter study of a new enzymatic method of cholesterol determination.
        Clin. Chem. Clin. Biochem. 1984; 22: 24
        • Takayama M.
        • Itoh S.
        • Nagasaki T.
        • Tanimizu I.
        A new enzymatic method for determination of serum choline-containing phospholipids.
        Clin. Chim. Acta. 1979; 79: 93
        • Kostner G.M.
        • Molinari E.
        • Piedler P.
        Evaluation of a new HDLZ/HDL3 quantitation method based on precipitation with polyethylene glycol.
        Clin. Chim. Acta. 1985; 148: 139
        • Mancini G.
        • Carbonara A.O.
        • Heremaus J.F.
        Immunchemical quantitation of antigens by single radial immunodiffusion.
        in: Immunchemistry. Vol. 2. Pergamon Press, Oxford1965: 235-254
        • Luley C.
        • Peredi F.
        • Zuckhold H.D.
        • Prellwitz W.
        Lp(a) Evaluation of a new radioimmunoassay.
        J. Clin. Chem. Clin. Biochem. 1990; (in press)
        • Friedewald W.T.
        • Levy R.I.
        • Fredrickson D.S.
        Estimation of plasma low density lipoprotein cholesterol concentration without use of the preparative ultracentrifuge.
        Clin. Chem. 1972; 18: 499
        • Li J.Z.
        • Wang J.J.
        Reference concentration of apo A-I and apo B.
        Natl. Med. J. China. 1986; 66: 531
        • Wang S.P.
        • Zhen J.H.
        • Wan F.Y.
        Subunite HDL and the mean in CHD.
        Acta Acad. Med. Tongji (Wuhan). 1987; 3: 189
        • Deng Y.Z.
        • Feng Z.C.
        • Dia G.Z.
        Serum apo A-1, apo A-II and apo B in the patients with CHD and their clinical significance.
        Acta Acad. Med. Tongji (Wuhan). 1987; 4: 237
        • Deng Y.Z.
        • Feng Z.C.
        • Zeng J.H.
        Vergleichende Studie fiber Risikofaktoren bei koronarer Herzkrankheit in Wuhan and bei deutschen Arbeitern.
        Acta Acad. Med. Tongji (Wuhan). 1986; 2: 77
        • Assmann G.
        • Schulte H.
        Prediction and early detection of coronary heart disease.
        in: Hauss W.H. Clinical implications of recent research results in arteriosclerosis. Abhandlungen der Rheinisch-Westfalischen Akademie der Wissenschaften, Second Munster International Arteriosclerosis Symposium. Westdeutscher Verlag, Opladen1982: 14
        • The Lipid Research Clinics Program Epidemiology Committee
        Plasma lipid distribution in selected North American populations: The Lipid Research Clinics Program Prevalence Study.
        Circulation. 1979; 60: 427
        • Hu Z.L.
        • Zhou J.T.
        A comparative study to CHD risk factor in the bus drivers.
        Occupat. Hyg. J. China. 1984; 2: 316
        • Zung H.Z.
        • Chen G.Z.
        • Han Q.Q.
        • Chen B.
        The concentration of blood lipids relationship with the current nutrition in 3.312 residents of Shanghai City.
        Natl. Med. J. China. 1986; 66: 585
        • Zhang S.-S.
        The Current Nutrition Standard and the Future Diet Constitution Plan of Tianjin Residents.
        Publication of the Tianjin Sanitation & Diseases Prevention Center, 1987 (An english translation by Chen Yao-Jii is available from the author.)
      1. Ernahrungsbericht 1988.
        Deutsche Gesellschaft fur Ernahrung e.V. 1988; (Frankfurt): 22
        • Goto Y.
        Cholesterol level of Japanese in the past twenty years and primary prevention study by dextran sulfate [MDS].
        in: Fidge N.H. Nestel P.J. Proc. 7th Int. Symp. Atherosclerosis. Atherosclerosis. VII. Excerpta Medica, Amsterdam1986: 9