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Abstract
This paper reviews the available evidence concerning the atherogenic potential of
carbon monoxide. The evidence comes from two different types of studies — epidemiology
studies on populations of humans chronically exposed to carbon monoxide, and animal
studies conducted under conditions of controlled exposure to carbon monoxide. Data
from both epidemiology and animal studies suggest that carbon monoxide is not atherogenic.
Therefore, the increased levels of atherosclerosis associated with smoking as reported
in epidemiology studies of human smokers probably cannot be attributed to CO exposure.
Keywords
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Article info
Publication history
Accepted:
December 18,
1992
Received in revised form:
December 3,
1992
Received:
October 28,
1992
Identification
Copyright
© 1993 Published by Elsevier Inc.