Distribution of lipid variables in subjects in Belfast, Northern Ireland and Taiyuan, P R China

      This paper is only available as a PDF. To read, Please Download here.


      To compare the plasma lipid, lipoprotein and apolipoprotein profiles of people of Chinese and European origin, a sample of 151 male Chinese subjects was selected from Taiyuan, Shanxi Province, P R China to 202 broadly age-matched subjects in Belfast who were selected as controls in a case-control study of myocardial infarction. Mean total cholesterol (TC) was 6.15 mmol/l in Belfast and 4.28 mmol/1 in Taiyuan. Low density lipoprotein cholesterol (LDL) was much higher in Belfast. High density lipoprotein cholesterol (LDL) was also higher in Belfast than in Taiyuan but the ratio of HDL to TC was lower in Belfast than Taiyuan. Triglyceride (TG) levels were similiar and this was reflected in the relatively high level of apolipoprotein E (apo E) in the Chinese sample.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Atherosclerosis
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Kannel W.B.
        • Castelli W.P.
        Is the serum total cholesterol an anachronism?.
        Lancet. 1979; 2: 905
        • Bainton D.
        • Miller N.E.
        • Bolton L.H.
        • Yarnell J.W.G.
        • Sweetnam P.M.
        • Baker I.A.
        • Lewis B.
        • Elwood P.C.
        Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men.
        Br. Heart J. 1992; 68: 60
        • Avogaro P.
        • Bittolo Bon G.
        • Cazzolato G.
        • Rorai E.
        Relationship between apolipoproteins and chemical components of lipoproteins in survivors of myocardial infarction.
        Atherosclerosis. 1980; 37: 69
        • Parra H.J.
        • Arveiler D.
        • Evans A.E.
        • et al.
        A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease — The ECTIM study.
        Atheroscl. Thromb. 1992; 12: 701
        • Fisher M.
        • Levine P.H.
        • Weiner B.
        • et al.
        The effect of vegetarian diets on plasma lipid and platelet levels.
        arch. Intern. Med. 1986; 146: 1193
        • Sacks F.M.
        • Ornish D.
        • Rosner B.
        • McLanahan S.
        • Castelli W.P.
        • Kass E.H.
        Plasma lipoprotein levels in vegetarians — the effect of ingestion of fats from dairy products.
        J. Am. Med. Assoc. 1985; 254: 1337
        • Thorogood M.
        • Carter R.
        • Benfield L.
        • McPherson K.
        • Mann J.I.
        Plasma lipids and lipoprotein cholesterol concentrations in people with different diets in Britain.
        Br. Med. J. 1987; 295: 251
        • Masarei J.R.L.
        • Robertson K.
        • Rouse I.L.
        • Vandongen R.
        • Lynch W.J.
        • Beilin L.J.
        Vegetarian diets, lipid and cardiovascular risk.
        Aust. NZ J. Med. 1984; 14: 400
        • Burslem J.
        • Schonfeld G.
        • Howald M.A.
        • Weidman S.W.
        • Miller J.P.
        Plasma apoprotein and lipoprotein lipid levels in vegetarians.
        Metabolism. 1978; 27: 711
        • Gear J.S.
        • Mann J.I.
        • Thorgood M.
        • Carter R.
        • Jelfs S.
        Biochemical and haematological variables in vegetarians.
        Br. Med. J. 1980; 280: 1415
        • Mancini M.
        • Mattock
        • Rabaya E.
        • Chait A.
        • Lewis B.
        Studies in the mechanisms of carbohydrate—induced lipaemia in normal men.
        Atherosclerosis. 1973; 17: 445
        • Lock D.R.
        • Varhol A.
        • Grimes S.
        • Patsch W.
        • Schonfeld G.
        Apolipoprotein E levels in vegetarians.
        Metabolism. 1982; 31: 917
        • The Principal Investigators of the MONICA Project
        WHO MONICA Project. Geographical variation in mortality from cardiovascular diseases.
        W. H. Stat. Q. 1987; 40: 171
        • Alaupovic P.
        • Lee D.M.
        • McConathy W.J.
        Studies on the composition and structure of plasma lipoproteins. Distribution of lipoprotein families in major density classes of normal human plasma liopoproteins.
        Biochim. Biophys. Acta. 1972; 260: 689
        • Koren E.
        • Puchois P.
        • Alaupovic P.
        • Fesmire J.
        • Kandoussi A.
        • Fruchart J.C.
        Quantification of two different types of apolipoprotein AI containing lipoprotein particles in plasma by enzymelinked differential-antibody immunosorbentassay.
        Clin. Chem. 1987; 33: 38
        • Vu-Dac N.
        • Mezdour H.
        • Parra H.J.
        • Luc G.
        • Luyeye I.
        • Fruchart J.C.
        A selective bi-site immunoenzymatic procedure for human Lp(a) lipoprotein quan tification using monoclonal antibodies against Apo(a) and ApoB.
        J. Lipid. Res. 1989; 30: 1437
        • Parra H.J.
        • Mezdour H.
        • Ghalim N.
        • Bard J.M.
        • Fruchart J.C.
        Differential electroimmunoassay of human LpAI lipoprotein particles on ready-to-use plate.
        Clin. Chem. 1990; 36: 1431
        • Truswell A.S.
        • Mann J.I.
        Epidemiology of serum lipids in Southern Africa.
        Atherosclerosis. 1972; 16: 15
        • Huang Liu
        Analysis, future improvement and mediumlong term project of residents diet and nutrition state in Shanxi Province, P R China.
        in: Selection of research papers in the North China Dietary Conference. Chinese Scientific and Technologic Press, Beijing1990: 221-227
        • McClean R.
        • McCrum E.
        • Scally G.
        • et al.
        Dietary patterns in the Belfast MONICA Project.
        in: Proc. Nutr. Soc.49. 1990: 297
        • WHO MONICA Project Principal Investigators
        The WHO MONICA project: A worldwide monitoring system for cardiovascular disease.
        W. H. Stat. Ann. 1989; 72: 149
        • Chen Z.
        • Petoo R.
        • Collins R.
        • MacMahon S.
        • Lu J.
        • Li W.
        Serum cholesterol concentration and coronary heart disease in a population with low cholesterol concentrations.
        Br. Med. J. 1991; 303: 276
        • Thompson G.R.
        A handbook of hyperlipidaemia MSO. Current Science Ltd, London1989: 13
        • Rhoads G.G.
        • Dahlen G.
        • Berg K.
        • Morton N.E.
        • Dannenberg A.L.
        Lp(a) lipoprotein as a risk factor for MI.
        J. Am. Med. Assoc. 1986; 256: 2540
        • Utermann G.
        The mysteries of lipoprotein (a).
        Science. 1989; 246: 904
        • Parra H.J.
        • Luyéyé I.
        • Bouramoué C.
        • Demarquilly C.
        • Fruchart J.C.
        Black-White differences in serum Lp(a) lipoprotein levels.
        Clin. Chim. Acta. 1987; 167: 27
        • Sandholzer C.
        • Holmann D.M.
        • Saba N.
        • Sigurdsson G.
        • Lacker C.
        • Csaszar A.
        Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups.
        Hum, Genet. 1991; 86: 607