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Abstract
A new prospective study of non-institutionalised Australian elderly 60 years and over
commenced in Dubbo in 1988, comprising 1236 men and 1569 women. This report examines
clinical and socio-demographic predictors of coronary heart disease (CHD) over a median
62 months follow-up. CHD incidence rates (ICD-9-CM codes 410–414) were higher in men
than women until 79 years, thereafter, the rates for recurrent disease were higher
in women. Incidence rates for recurrent disease were three-fold those for initial
disease. In Cox proportional hazards analysis, the significant predictors of all CHD
were: advancing age, prior CHD (relative risk (RR) = 2.50 and 2.15 in men and women,
respectively), use of anti-hypertensive medication (RR = 1.92 and 1.75 in men and
women, respectively), diabetes (RR = 1.67 and 1.53 in men and women, respectively),
serum cholesterol, low density lipoprotein cholesterol and serum apo B in men (RR
= 1.24), serum triglycerides in women (RR = 1.23), high density lipoprotein cholesterol
in men (RR = 0.82), lipoprotein(a) in women (RR = 1.99), and poorer self-rating of
health (RR = 1.48 and 1.93 in men and women, respectively). Serum cholesterol was
not predictive of CHD in men beyond 74 years. Isolated systolic hypertension predicted
CHD in women (RR = 3.76), but not in men (RR = 1.20). The findings highlight key risk
factors for CHD in the elderly.
Keywords
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Article info
Publication history
Accepted:
March 13,
1995
Received in revised form:
March 7,
1995
Received:
December 20,
1994
Identification
Copyright
© 1995 Published by Elsevier Inc.
