European Lipoprotein Club: Report of the 26th ELC Annual Conference, Tutzing, 8–11 September 2003

      The 26th meeting of the European Lipoprotein club was held from 8 to 11 September 2003 at the evangelische akademie in Tutzing and attended by 110 participants from 15 different countries. Dr. J.D. Horton (Dallas, USA) presented the keynote lecture. He discussed the role of sterol regulatory element-binding proteins (SREBPs) in the regulation of cholesterol and fatty acid synthesis and their role in the metabolic syndrome. The first session was focused upon HDL function and regulation, and opened with an overview on regulation of reverse cholesterol transport by Arnold von Eckardstein (Zürich, Switzerland). The next session was focused on lipid metabolism in the brain and was introduced by a lecture from Ingemar Björkhem (Stockholm, Sweden) on “Brain cholesterol—long and intensive secret life behind a barrier”. Session III highlighted the state of the art on gene environment action and was opened by Steve Humphries (London) presenting new aspects of smoking interaction with apo E on cardiovascular risk. This was followed by a session on cellular lipid transport. The leading speaker was Bert Groen (Amsterdam, The Netherlands) who updated the audience on the close relationship between reverse cholesterol transport and bile acid metabolism. Inflammation and immune response in atherosclerosis was the topic of session V. Ron Law (Los Angeles, USA) opened this session with a presentation on new targets for PPAR-gamma in the vessel wall. The meeting was closed with the well-known “Varia” session. The young investigator award was this year presented to Arja Kreeft (Leiden, The Netherlands) for her presentation on “identification of dietary response genes in hyperlipidemic mouse models by gene expression profiling.
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