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Definition of the acronym PRIME

      I wonder how many of your readers were puzzled by how Luc et al. [
      • Luc G.
      • Arveiler D.
      • Evans A.
      • et al.
      On behalf of the PRIME Study Group: circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: The PRIME Study.
      ] defined PRIME in their recent article. The authors defined PRIME as the Epidemiological Study of Myocardial Infarction [
      • Luc G.
      • Arveiler D.
      • Evans A.
      • et al.
      On behalf of the PRIME Study Group: circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: The PRIME Study.
      ]. I would challenge anybody to explain how PRIME stands for Epidemiological Study of Myocardial Infarction! Before you receive many more letters-to-the-editor from your perplexed readers, I wish to come to your aid by indicating that PRIME stands for ‘etude PRospective de l’Infarctus du MyocardE’ [
      • Cheng T.O.
      • Julian D.
      Acronyms of cardiologic trials—2002.
      ]. As most of the participants of the study are French, it is easy to understand why the name of the study is also in French.
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      References

        • Luc G.
        • Arveiler D.
        • Evans A.
        • et al.
        On behalf of the PRIME Study Group: circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: The PRIME Study.
        Atherosclerosis. 2003; 170: 169-176
        • Cheng T.O.
        • Julian D.
        Acronyms of cardiologic trials—2002.
        Int. J. Cardiol. 2003; 91: 261-351
        • Cheng T.O.
        What’s in an acronym?.
        Am. J. Cardiol. 1994; 73: 932
        • Cheng T.O.
        Acronyms of clinical trials in cardiology—1994.
        Am. J. Cardiol. 1994; 74: 79-94
        • Cheng T.O.
        Non-English acronyms must be explained in their native languages.
        Int. J. Cardiol. 1997; 61: 199
        • Cheng T.O.
        Non-English acronyms have to be explained in their native languages.
        Am. J. Cardiol. 2000; 85: 280
        • Cheng T.O.
        Use of unexplained acronyms in specialty journals.
        Int. J. Cardiol. 1994; 46: 185-188