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Effects of chronic microbial infection on atherosclerosis

      The recognition of atherosclerosis as an inflammatory disease in its genesis, progression and ultimate clinical manifestations has created an interesting area of vascular research. We read with great interest the paper by Beck et al. [
      • Beck J.D.
      • Eke P.
      • Lin D.
      • et al.
      Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults.
      ] speculating over a possible link between atherogenesis and microbial risk factors. The paper offers a valid contribution to the understanding of mechanisms underlying atherogenesis. Anyway, we feel that some additional details could add a value to the data presented in that paper.
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      References

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        • Eke P.
        • Lin D.
        • et al.
        Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults.
        Atherosclerosis. 2005; 183: 342-348
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        • et al.
        Correlation between detection rates of periodontopathic bacterial DNA in coronary stenotic artery plaque [corrected] and in dental plaque samples.
        J Clin Microbiol. 2004; 42: 1313-1315
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        Multiple infections in carotid atherosclerotic plaques.
        Am Heart J. 1999; 138: S534-S536
        • Paciaroni M.
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        Is ultrasound examination sufficient in the evaluation of patients with internal carotid artery severe stenosis or occlusion?.
        Cerebrovascular Dis. 2003; 15: 173-176