Objectives: HIV-1 Nef is a pleiotropic modulator of various cellular cell surface receptors.
Our lab has established that HIV reduces cholesterol efflux, a major mechanism of
atheroprotection, in peripheral tissues through the action of Nef. Nef impairs the
functionality of ABCA1 and induces ABCA1 degradation. In these studies we investigated
the mechanism of this Nef activity.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to AtherosclerosisAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Publication history
EAS-0413
Identification
Copyright
© 2014 Published by Elsevier Inc.
