Objectives: MDCO216 is a complex of dimeric apoA-IMilano (apoA-IM) and POPC, shown to reduce atherosclerotic plaque burden. Here we studied the effect of incubation of human plasma or serum with MDCO216 on cholesterol efflux capacity from J774 cells, as well as on various HDL subfractions measured by ELISA, 2D-electrophoresis and NMR.
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© 2014 Published by Elsevier Inc.