Objectives: MDCO216 is a complex of dimeric apoA-IMilano (apoA-IM) and POPC, shown to reduce
atherosclerotic plaque burden. Here we studied the effect of incubation of human plasma
or serum with MDCO216 on cholesterol efflux capacity from J774 cells, as well as on
various HDL subfractions measured by ELISA, 2D-electrophoresis and NMR.
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EAS-0865
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© 2014 Published by Elsevier Inc.