Objectives: Cholesterol efflux from peripheral macrophages into high-density lipoprotein (HDL)
is a key atheroprotective function of HDL. The capacity of human serum or total HDL
to accept cholesterol has been linked with cardiovascular morbidity. Our aim was to
study 1) how cholesterol efflux into total HDL, HDL2 and HDL3 (total HDL-, HDL2- and
HDL3-efflux, respectively) is associated with a phenotype of low HDL-cholesterol (HDL-C)
and early coronary heart disease (CHD) 2) how the efflux parameters are related to
each other 3) which cardiometabolic factors predict efflux.
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EAS-0578
Identification
Copyright
© 2014 Published by Elsevier Inc.
