66 - Lipid-lowering therapy| Volume 235, ISSUE 2, e262-e263, August 2014

Vascular effects of sterols, oxysterols, phytosterols, and oxyphytosterols in apoE-/-mice

      Objectives: Plant sterol esters (PSE) are used as food supplements to reduce serum cholesterol levels. Both plant sterols and cholesterol are prone to oxidation and convert to oxysterols and oxyphytosterols. The effects of oxysterols and oxyphytosterols on reactive oxygen species (ROS), endothelial function and atherogenesis in apoE-/-mice are not known.
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