Highlights
- •The study showed that MS and its components were positively correlated with baPWV.
- •Monitoring baPWV for MS patients is helpful to identify early stage of atherosclerosis.
- •The development of atherosclerosis can be delayed by controlling MS.
Abstract
Background
Brachial-ankle pulse wave velocity (baPWV) can reflect both central and peripheral
arterial stiffness. Metabolic syndrome (MS) and its components may increase arterial
stiffness and the risks of cardiovascular diseases. However, the correlation of MS
and its components with arterial stiffness has not been not well studied. The aim
of this study was to investigate the correlation between MS/its components and arterial
stiffness by the measurement of baPWV in south China population.
Methods
A total of 8599 subjects were selected from those who underwent health examination
in our hospital. MS was defined by Joint Scientific Statement. BaPWV, waist circumference,
blood pressure (BP), fasting plasma glucose (FPG), lipid profile and serum uric acid
(UA) were measured. The relationship between baPWV and MS/its components was analyzed.
Results
BaPWV was significantly higher in the subjects with MS than in those without MS (P < 0.001
for both genders). By multivariate regression analysis, all the metabolic components
were correlated to baPWV in the male and female subjects except low HDL-C and high
UA in the male group. BP and FPG had the strongest correlation factors. The values
of baPWV were positively correlated with the advanced age (P < 0.001) and the values
of the MS components, and this correlation was stronger in the females than in the
males (P < 0.001).
Conclusion
Metabolic syndrome and its individual components were positively correlated with baPWV.
Monitoring baPWV is helpful to identify early stage of arterial stiffness in those
people with MS.
Keywords
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Article info
Publication history
Published online: March 21, 2015
Accepted:
March 18,
2015
Received in revised form:
March 5,
2015
Received:
January 4,
2015
Identification
Copyright
© 2015 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
