Antioxidant response element cytoprotective response in aortic endothelial cells coordinated by transcription factor Nrf2 is regulated through frequency-modulated translocational oscillations

      Aim: To examine how Nrf2 signals cell stress status and regulates transcription to maintain homeostasis and respond to challenges of endothelial cell dysfunction in cardiovascular disease. Nrf2 regulates a battery of protective genes by binding to regulatory anti-oxidant response elements (AREs).
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