Vascular biology II| Volume 241, ISSUE 1, e43, July 2015

New mechanisms for steroid pro-atherogenic action: Up regulation of macrophage LDL receptors, down regulation of cholesterol efflux transporters and increase in intracellular cholesterol stores

      Aim. We recently showed that steroids are pro-athrogenic not only because of metabolic effects, but also through the direct induction of cholesterol accumulation in human macrophages. In this study we investigated the molecular mechanisms underlying such effect.
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