Objectives: In chronic kidney disease (CKD), the decline of estimated glomerular filtration rate
(eGFR) associates with increased cardiovascular mortality, which is not fully explained
by the dyslipidemia developed by these subjects. Our aim was to study the association
of eGFR decline with changes in lipoprotein composition, size and selected functionalities:
for HDL, the in vitro cholesterol efflux capacity (CEC) and its antioxidant effects, a potential athero-protective
mechanism, and, for LDL, the binding to arterial proteoglycans, an atherogenic mechanism.
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Publication history
EAS16-0812 Workshop 2.1: Lipoproteins and Extracellular Matrix
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© 2016 Published by Elsevier Inc.
