Objectives: Obesity is a well-established risk factor for cardiovascular disease (CVD). Approximately
45% of this risk is mediated via the traditional risk factors blood pressure, glucose
and cholesterol. The mechanisms underlying the remaining part of this risk are unclear.
Inflammation is a candidate because adipocytes excrete cytokines that may induce a
low-grade inflammatory state. We investigated to what extent inflammation mediates
the associations of overall and visceral adiposity with atherosclerosis.
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Article Info
Publication History
EAS16-0591 Novel Pathways in Atherosclerosis
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© 2016 Published by Elsevier Inc.