Objectives: Recruitment of pro-inflammatory M1 macrophages into adipose-tissue during obesity
results in localised inflammation. Adipocytes are a major store of cholesterol in
the body while macrophage efflux is critical to protect against atherosclerosis. This
study investigated the effects of inflammation on cholesterol efflux from macrophages
and adipocytes to understand the implications of obesity-associated inflammation on
cellular cholesterol trafficking.
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Publication history
EAS16-0596 Lipoproteins and Lipid Metabolism: HDL
Identification
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© 2016 Published by Elsevier Inc.