We read with particular interest the study by Antoniewicz et al. published in Atherosclerosis, on the acute effects of e-cigarette use on endothelial progenitor cell (EPC) levels
[
[1]
]. The authors suggest that the increase in EPCs may indicate some form of acute vascular
injury. Since earlier work by the same research group showed an acute transient elevation
in EPC after smoking, their interpretation of the findings after e-cigarette use is
based on a similar response observed with tobacco cigarettes [
[1]
].Keywords
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References
- Electronic cigarettes increase endothelial progenitor cells in the blood of healthy volunteers.Atherosclerosis. 2016; 255: 179-185https://doi.org/10.1016/j.atherosclerosis.2016.09.064
- Endothelial progenitor cells in cardiovascular disorders.J. Am. Coll. Cardiol. 2007; 49: 741-752https://doi.org/10.1016/j.jacc.2006.09.050
- Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers.Arterioscler. Thromb. Vasc. Biol. 2004; 24: 1442-1447https://doi.org/10.1161/01.ATV.0000135655.52088.c5
- Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability.Arterioscler. Thromb. Vasc. Biol. 2010; 30: 869-877https://doi.org/10.1161/ATVBAHA.109.200618
- Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium.Am. J. Clin. Nutr. 2011; 93: 267-274https://doi.org/10.3945/ajcn.110.006866
- Mobilization of endothelial progenitor cells with exercise in healthy individuals: a systematic review.Arq. Bras. Cardiol. 2012; 98: 182-191https://doi.org/10.1590/S0066-782X2012000200012
- Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers.Circ. J. 2006; 70: 1052-1057https://doi.org/10.1253/circj.70.1052
- Blood pressure control in smokers with arterial hypertension who switched to electronic cigarettes.Int. J. Environ. Res. Public Health. 2016; 13: 1123https://doi.org/10.3390/ijerph13111123
Article info
Publication history
Published online: December 22, 2016
Accepted:
December 14,
2016
Received:
December 11,
2016
Identification
Copyright
© 2016 Elsevier Ireland Ltd. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Electronic cigarettes increase endothelial progenitor cells in the blood of healthy volunteersAtherosclerosisVol. 255
- PreviewThe use of electronic cigarettes is increasing dramatically on a global scale and its effects on human health remain uncertain. In the present study, we measured endothelial progenitor cells (EPCs) and microvesicles (MVs) in healthy young volunteers following short-term exposure to inhalation of e-cigarette vapor (ECV) to determine vascular changes.
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- Reply to: “Endothelial progenitor cell release is usually considered a beneficial effect: Problems in interpreting the acute effects of e-cigarette use”AtherosclerosisVol. 258
- PreviewVascular injury has long been known to be the main cause for mobilization of endothelial progenitor cells (EPCs) [1–3]. It has been proven that the strongest factor mobilizing EPCs is hypoxia in the vascular wall, causing the release of vascular endothelial growth factor 2 (VEGF-2) and stromal derived factor 1 (SDF-1) [1–3]. These two factors bind to receptors on EPCs, initiating mobilization and homing to the site of lesion. Therefore, it is not surprising that in cases of obvious vascular damage, such as in myocardial infarction or stroke, EPCs are highly elevated [1–3].
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