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Effect of spontaneous changes in dietary components and lipoprotein(a) levels: Data from the Brisighella Heart Study

      We carefully read the publication of Perrot and collaborators published in Atherosclerosis. [
      • Perrot N.
      • Verbeek R.
      • Sandhu M.
      • Boekholdt S.M.
      • Hovingh G.K.
      • Wareham N.J.
      • Khaw K.T.
      • Arsenault B.J.
      Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: the EPIC-Norfolk prospective population study.
      ] Reporting data from the well-characterized EPIC-Norfolk population study, Perrot et al. predictably concluded that the management of the main cardiovascular risk factors has to be recommended also in subjects with high lipoprotein(a) [Lp(a)]. Even if Lp(a) levels tend to remain stable throughout life, some nutrients were demonstrated to mildly affect its serum concentrations. Authors only mentioned some dietary intervention studies, but we hypothesize Lp(a) could be also affected by spontaneous changes in the food daily intake, which were never investigated up to now.

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      References

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        Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: the EPIC-Norfolk prospective population study.
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