Aim: The ATP-binding cassette transporter A1 (ABCA1) facilitates the efflux of cholesterol
and phospholipids to lipid-free apolipoprotein A1 and small dense high-density lipoproteins.
Various studies have shown that leukocyte ABCA1 is an anti-atherogenic factor. Dietary
cholesterol lowering stabilizes atherosclerotic lesions, however the role of ABCA1
in this process is unknown. Therefore, this study aims to investigate the effect of
leukocyte ABCA1 on diet-induced atherosclerotic lesions after withdrawal of the atherogenic
diet.
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© 2017 Published by Elsevier Inc.
