LDLR influence on CD4 T cells differentiation in mice and in familial hypercholesterolemia patients

      Aim: Expansion of CD4 T cells of the effector memory phenotype is known to correlate with atherosclerosis and disease progression. Here we investigate whether key players linking systemic and cellular lipid metabolism, such as the LDL-R, affect the differentiation and functionality of CD4+ T cells.
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