Aim: Carotid atherosclerosis plaque instability is increased by intraplaque hemorrhage
(IPH) and neovascularization. Oxidative stress is known to promote these two risk
factors and induce a vicious circle with IPH and neovascularization. Moreover, it
was shown that regular physical activity can reduce oxidative stress by increasing
antioxidant defenses whereas sedentary behavior can increase oxidative stress independently
to physical activity. The aim of this study was therefore to evaluate the effects
of both physical activity and sedentary behavior on the carotid plaque histological
characteristics and oxidative stress in patients at high-risk of stroke.
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© 2017 Published by Elsevier Inc.
